[5] Chelsea U21 2-0 Southampton U21 [16] 2024-04-26 18:00
Stadium: The Electrical Services Stadium Round: 20
Home History
| England U21 Premier League Cup | 2024/04/19 18:00 | Chelsea U21 v Fulham U21 | L | 0-4 |
| England Premier League 2 | 2024/04/12 18:00 | Crystal Palace U21 v Chelsea U21 | D | 2-2 |
| England Premier League 2 | 2024/04/08 17:00 | Aston Villa U21 v Chelsea U21 | W | 0-4 |
| England U21 Premier League Cup | 2024/03/30 13:00 | Leeds U21 v Chelsea U21 | W | 2-3 |
| England Premier League 2 | 2024/03/15 19:00 | Chelsea U21 v Nottm Forest U21 | L | 2-3 |
| England Premier League 2 | 2024/03/08 19:00 | Newcastle U21 v Chelsea U21 | W | 1-7 |
| England Premier League 2 | 2024/03/01 19:00 | Chelsea U21 v Arsenal U21 | L | 2-4 |
| England U21 Premier League Cup | 2024/02/26 19:00 | Chelsea U21 v Norwich U21 | W | 3-2 |
Away History
| England Premier League 2 | 2024/04/12 18:00 | Southampton U21 v Nottm Forest U21 | D | 1-1 |
| England Premier League 2 | 2024/04/05 18:00 | Norwich U21 v Southampton U21 | W | 0-2 |
| England Premier League 2 | 2024/03/15 19:00 | Southampton U21 v Crystal Palace U21 | W | 4-0 |
| England Premier League 2 | 2024/03/08 19:00 | Southampton U21 v Stoke U21 | W | 5-1 |
| England Premier League 2 | 2024/03/04 18:00 | West Brom U21 v Southampton U21 | D | 1-1 |
| England Premier League 2 | 2024/02/16 19:00 | Arsenal U21 v Southampton U21 | L | 4-2 |
| England Premier League 2 | 2024/01/29 19:00 | Leicester U21 v Southampton U21 | W | 1-2 |
| Premier League International Cup | 2024/01/24 19:00 | Southampton U21 v Celtic U21 | L | 1-3 |