Stadium: Carpenter–Haygood Stadium Round: 1
| NCAAF | 2022/10/08 19:00 | East Central Tigers v Henderson State Reddies | L | 31-10 |
| NCAAF | 2021/10/09 19:00 | Henderson State Reddies v East Central Tigers | W | 59-24 |
| NCAAF | 2019/10/19 19:00 | Henderson State Reddies v East Central Tigers | W | 48-17 |
| NCAAF | 2018/10/13 20:00 | East Central Tigers v Henderson State Reddies | W | 10-31 |
| NCAAF | 2022/11/12 20:00 | Henderson State Reddies v Ouachita Baptist Tigers | L | 37-40 |
| NCAAF | 2022/11/05 19:00 | Henderson State Reddies v Oklahoma Baptist Bison | W | 51-24 |
| NCAAF | 2022/10/29 19:00 | Southern Nazarene v Henderson State Reddies | W | 41-42 |
| NCAAF | 2022/10/22 19:00 | Henderson State Reddies v Arkansas Tech Wonder Boys | W | 35-19 |
| NCAAF | 2022/10/15 19:00 | Harding Bisons v Henderson State Reddies | W | 14-15 |
| NCAAF | 2022/10/08 19:00 | East Central Tigers v Henderson State Reddies | L | 31-10 |
| NCAAF | 2022/10/01 19:00 | Henderson State Reddies v Southeastern Oklahoma State Savage Storm | W | 31-23 |
| NCAAF | 2022/09/24 23:00 | Southern Arkansas Muleriders v Henderson State Reddies | L | 28-24 |
| NCAAF | 2022/11/12 20:00 | East Central Tigers v Southeastern Oklahoma State Savage Storm | W | 31-10 |
| NCAAF | 2022/11/05 19:00 | East Central Tigers v Arkansas Monticello Boll Weevils | W | 16-0 |
| NCAAF | 2022/10/27 23:00 | Ouachita Baptist Tigers v East Central Tigers | L | 28-18 |
| NCAAF | 2022/10/22 19:00 | East Central Tigers v Southwestern Oklahoma State Bulldogs | W | 42-28 |
| NCAAF | 2022/10/15 23:00 | Oklahoma Baptist Bison v East Central Tigers | W | 20-34 |
| NCAAF | 2022/10/08 19:00 | East Central Tigers v Henderson State Reddies | W | 31-10 |
| NCAAF | 2022/10/01 19:30 | Southern Arkansas Muleriders v East Central Tigers | W | 22-34 |
| NCAAF | 2022/09/24 23:00 | East Central Tigers v Northwestern Oklahoma State Rangers | W | 31-3 |