Stadium: William B. Greene Jr. Stadium Round: 1
Home Manager: George Quarles Away Manager:
| NCAAF | 2023/09/02 18:00 | East Tennessee State v Jacksonville State | L | 3-49 |
| NCAAF | 2022/11/19 17:00 | East Tennessee State v Mississippi State | L | 7-56 |
| NCAAF | 2022/11/12 18:00 | Western Carolina v East Tennessee State | L | 20-17 |
| NCAAF | 2022/10/29 17:30 | East Tennessee State v Wofford | L | 41-48 |
| NCAAF | 2022/10/22 19:30 | Samford v East Tennessee State | L | 55-45 |
| NCAAF | 2022/10/15 20:00 | East Tennessee State v Mercer | L | 33-55 |
| NCAAF | 2022/10/08 17:30 | East Tennessee State v VMI | W | 44-21 |
| NCAAF | 2022/10/01 19:00 | Tennessee Chattanooga v East Tennessee State | L | 24-16 |
| NCAAF | 2023/08/31 23:00 | Carson–Newman Eagles v Lynchburg Dragons | W | 35-3 |
| NCAAF | 2022/11/12 18:00 | Catawba College v Carson–Newman Eagles | W | 23-61 |
| NCAAF | 2022/11/05 19:00 | Carson–Newman Eagles v Virginia Wise Highland Cavaliers | W | 38-22 |
| NCAAF | 2022/10/29 17:00 | Emory And Henry Wasps v Carson–Newman Eagles | W | 7-21 |
| NCAAF | 2022/10/22 17:00 | Mars Hill Lions v Carson–Newman Eagles | L | 44-13 |
| NCAAF | 2022/10/15 22:00 | Carson–Newman Eagles v Erskine Flying Fleet | W | 37-0 |
| NCAAF | 2022/10/08 17:30 | Tusculum Pioneers v Carson–Newman Eagles | L | 34-6 |
| NCAAF | 2022/10/01 17:00 | Carson–Newman Eagles v Newberry Wolves | W | 24-14 |