Stadium: Pomoco Stadium Round: 1
| NCAAF | 2022/11/12 18:00 | Salisbury Sea Gulls v Christopher Newport Captains | L | 36-33 |
| NCAAF | 2022/11/05 17:00 | Christopher Newport Captains v Tcnj Lions | W | 24-21 |
| NCAAF | 2022/10/29 17:00 | Montclair State Red Hawks v Christopher Newport Captains | W | 13-14 |
| NCAAF | 2022/10/22 17:00 | Christopher Newport Captains v William Paterson Pioneers | W | 31-7 |
| NCAAF | 2022/10/15 16:00 | Kean Cougars v Christopher Newport Captains | W | 13-24 |
| NCAAF | 2022/10/01 17:00 | Christopher Newport Captains v Rowan Profs | W | 20-14 |
| NCAAF | 2022/09/24 18:00 | Christopher Newport Captains v Catholic Cardinals | W | 38-7 |
| NCAAF | 2022/09/17 23:00 | Christopher Newport Captains v The Apprentice School Builders | L | 35-38 |
| NCAAF | 2022/11/12 18:00 | Southern Virginia Knights v Brevard Tornados | L | 27-41 |
| NCAAF | 2022/11/05 17:00 | Lagrange Panthers v Southern Virginia Knights | W | 21-35 |
| NCAAF | 2022/10/29 17:00 | Southern Virginia Knights v Methodist Monarchs | L | 23-36 |
| NCAAF | 2022/10/22 17:00 | Belhaven Blazers v Southern Virginia Knights | L | 42-6 |
| NCAAF | 2022/10/15 17:00 | Southern Virginia Knights v Maryville Scots | L | 7-45 |
| NCAAF | 2022/10/08 16:00 | Greensboro Pride v Southern Virginia Knights | L | 38-28 |
| NCAAF | 2022/09/24 17:00 | Southern Virginia Knights v Nc Wesleyan Battling Bishops | L | 13-14 |
| NCAAF | 2022/09/17 17:00 | Randolph Macon Yellow Jackets v Southern Virginia Knights | L | 47-20 |