Stadium: Keystone Giants Stadium Round: 1
| NCAAF | 2022/10/01 16:00 | Keystone Giants v Gallaudet Bison | L | 44-52 |
| NCAAF | 2021/10/09 16:00 | Gallaudet Bison v Keystone Giants | L | 34-14 |
| NCAAF | 2022/11/12 17:00 | Dean Bulldogs v Keystone Giants | W | 44-45 |
| NCAAF | 2022/11/05 17:00 | Keystone Giants v Suny Maritime Privateers | W | 21-20 |
| NCAAF | 2022/10/22 16:00 | Keystone Giants v Castleton Spartans | L | 20-35 |
| NCAAF | 2022/10/15 16:00 | Anna Maria Amcats v Keystone Giants | W | 39-41 |
| NCAAF | 2022/10/08 17:00 | Alfred State Pioneers v Keystone Giants | L | 42-33 |
| NCAAF | 2022/10/01 16:00 | Keystone Giants v Gallaudet Bison | L | 44-52 |
| NCAAF | 2022/09/24 17:30 | Keystone Giants v Hobart Statesmen | L | 6-65 |
| NCAAF | 2022/09/17 17:00 | William Paterson Pioneers v Keystone Giants | L | 27-20 |
| NCAAF | 2022/11/19 17:00 | Delaware Valley Aggies v Gallaudet Bison | L | 59-0 |
| NCAAF | 2022/11/05 16:00 | Alfred State Pioneers v Gallaudet Bison | W | 22-36 |
| NCAAF | 2022/10/29 16:00 | Gallaudet Bison v Anna Maria Amcats | W | 27-13 |
| NCAAF | 2022/10/22 17:00 | Gallaudet Bison v Suny Maritime Privateers | L | 24-26 |
| NCAAF | 2022/10/15 16:00 | Dean Bulldogs v Gallaudet Bison | W | 23-26 |
| NCAAF | 2022/10/08 16:00 | Gallaudet Bison v Castleton Spartans | W | 20-17 |
| NCAAF | 2022/10/01 16:00 | Keystone Giants v Gallaudet Bison | W | 44-52 |
| NCAAF | 2022/09/17 16:00 | University of New England Noreasters v Gallaudet Bison | W | 31-34 |