Stadium: Hardee-McGee Field at Harris Stadium Round: 1
| NCAAF | 2022/11/12 18:00 | Trinity Tigers v Sewanee Tigers | L | 38-0 |
| NCAAF | 2022/11/05 18:30 | Sewanee Tigers v Berry Vikings | L | 14-63 |
| NCAAF | 2022/10/29 19:00 | Rhodes Lynx v Sewanee Tigers | L | 33-6 |
| NCAAF | 2022/10/22 23:00 | Sewanee Tigers v Birmingham Southern Panthers | L | 3-47 |
| NCAAF | 2022/10/15 18:00 | Hendrix Warriors v Sewanee Tigers | L | 48-21 |
| NCAAF | 2022/10/08 17:00 | Centre Colonels v Sewanee Tigers | L | 35-16 |
| NCAAF | 2022/10/01 18:00 | Sewanee Tigers v Millsaps Majors | L | 27-30 |
| NCAAF | 2022/09/17 18:00 | Sewanee Tigers v Westminster Blue Jays | W | 41-6 |
| NCAAF | 2022/11/12 18:00 | Belhaven Blazers v Maryville Scots | W | 22-25 |
| NCAAF | 2022/10/29 18:00 | Maryville Scots v Brevard Tornados | L | 21-24 |
| NCAAF | 2022/10/22 17:00 | Maryville Scots v Nc Wesleyan Battling Bishops | W | 61-7 |
| NCAAF | 2022/10/15 17:00 | Southern Virginia Knights v Maryville Scots | W | 7-45 |
| NCAAF | 2022/10/08 17:00 | Lagrange Panthers v Maryville Scots | W | 17-56 |
| NCAAF | 2022/10/01 17:00 | Maryville Scots v Huntingdon Hawks | L | 28-42 |
| NCAAF | 2022/09/24 16:00 | Greensboro Pride v Maryville Scots | W | 17-37 |
| NCAAF | 2022/09/17 17:00 | Maryville Scots v Shenandoah Hornets | L | 29-34 |