Stadium: Pete FioRito Stadium at McKinzie Field Round: 1
| NCAAF | 2019/09/07 23:00 | Eureka Red Devils v Knox Prairie Fire | W | 42-28 |
| NCAAF | 2018/09/01 18:00 | Knox Prairie Fire v Eureka Red Devils | W | 24-49 |
| NCAAF | 2022/11/05 17:00 | St Norbert Green Knights v Eureka Red Devils | L | 20-7 |
| NCAAF | 2022/10/29 18:00 | Lakeland Muskies v Eureka Red Devils | L | 26-17 |
| NCAAF | 2022/10/22 23:00 | Eureka Red Devils v Wisconsin Lutheran Warriors | L | 35-51 |
| NCAAF | 2022/10/15 23:00 | Eureka Red Devils v Aurora Spartans | L | 13-72 |
| NCAAF | 2022/10/08 18:00 | Concordia Wisconsin Falcons v Eureka Red Devils | L | 23-20 |
| NCAAF | 2022/10/01 18:00 | Concordia Chicago Cougars v Eureka Red Devils | W | 13-27 |
| NCAAF | 2022/09/24 21:00 | Eureka Red Devils v Benedictine Eagles | L | 10-58 |
| NCAAF | 2022/09/17 18:00 | Eureka Red Devils v Rockford Regents | W | 31-14 |
| NCAAF | 2022/11/12 18:00 | Knox Prairie Fire v Monmouth Scots | L | 0-56 |
| NCAAF | 2022/11/05 18:00 | Cornell Rams v Knox Prairie Fire | W | 27-31 |
| NCAAF | 2022/10/29 18:00 | Lawrence Vikings v Knox Prairie Fire | W | 0-35 |
| NCAAF | 2022/10/22 18:00 | Knox Prairie Fire v Illinois College Blueboys | L | 10-20 |
| NCAAF | 2022/10/15 18:00 | Knox Prairie Fire v Grinnell Pioneers | W | 28-7 |
| NCAAF | 2022/10/08 18:00 | Beloit Buccaneers v Knox Prairie Fire | W | 25-34 |
| NCAAF | 2022/10/01 18:00 | Knox Prairie Fire v Chicago Maroons | L | 14-50 |
| NCAAF | 2022/09/17 19:00 | Lake Forest Foresters v Knox Prairie Fire | L | 48-14 |