Stadium: otterbein memorial stadium Round: 1
| NCAAF | 2022/09/03 18:00 | Ohio Wesleyan Battling Bishops v Otterbein Cardinals | W | 13-21 |
| NCAAF | 2021/09/04 16:00 | Otterbein Cardinals v Ohio Wesleyan Battling Bishops | L | 28-32 |
| NCAAF | 2019/09/07 18:00 | Ohio Wesleyan Battling Bishops v Otterbein Cardinals | L | 22-10 |
| NCAAF | 2018/09/01 17:30 | Otterbein Cardinals v Ohio Wesleyan Battling Bishops | W | 10-7 |
| NCAAF | 2022/11/12 18:30 | John Carroll Blue Streaks v Otterbein Cardinals | L | 62-7 |
| NCAAF | 2022/11/05 17:30 | Otterbein Cardinals v Ohio Northern Polar Bears | L | 7-42 |
| NCAAF | 2022/10/29 18:00 | Otterbein Cardinals v Mount Union | L | 0-59 |
| NCAAF | 2022/10/22 18:00 | Baldwin Wallace Yellow Jackets v Otterbein Cardinals | L | 35-14 |
| NCAAF | 2022/10/08 17:30 | Muskingum Muskies v Otterbein Cardinals | L | 41-35 |
| NCAAF | 2022/10/01 18:00 | Otterbein Cardinals v Capital Crusaders | W | 35-28 |
| NCAAF | 2022/09/24 18:00 | Otterbein Cardinals v Marietta Pioneers | L | 10-27 |
| NCAAF | 2022/09/17 18:00 | Wilmington Quakers v Otterbein Cardinals | L | 32-26 |
| NCAAF | 2022/11/12 18:00 | Ohio Wesleyan Battling Bishops v Hiram Terriers | W | 47-21 |
| NCAAF | 2022/11/05 17:00 | Wittenberg Tigers v Ohio Wesleyan Battling Bishops | W | 7-14 |
| NCAAF | 2022/10/29 23:00 | Ohio Wesleyan Battling Bishops v Oberlin Yeomen | W | 77-0 |
| NCAAF | 2022/10/22 17:00 | Ohio Wesleyan Battling Bishops v Depauw Tigers | L | 21-22 |
| NCAAF | 2022/10/15 17:00 | Wabash Little Giants v Ohio Wesleyan Battling Bishops | L | 41-24 |
| NCAAF | 2022/10/08 18:00 | Ohio Wesleyan Battling Bishops v Denison Big Red | W | 41-7 |
| NCAAF | 2022/10/01 17:00 | Wooster Scots v Ohio Wesleyan Battling Bishops | W | 7-35 |
| NCAAF | 2022/09/24 17:00 | Kenyon Lords v Ohio Wesleyan Battling Bishops | W | 14-41 |