Stadium: Bernlohr Stadium, CapitalUniversity Round: 1
| NCAAF | 2022/11/12 18:30 | Capital Crusaders v Heidelberg Student Princes | L | 30-44 |
| NCAAF | 2022/11/05 17:30 | Marietta Pioneers v Capital Crusaders | L | 50-14 |
| NCAAF | 2022/10/29 17:30 | Capital Crusaders v Baldwin Wallace Yellow Jackets | L | 7-48 |
| NCAAF | 2022/10/22 17:30 | John Carroll Blue Streaks v Capital Crusaders | L | 42-10 |
| NCAAF | 2022/10/15 17:30 | Capital Crusaders v Mount Union | L | 14-49 |
| NCAAF | 2022/10/01 18:00 | Otterbein Cardinals v Capital Crusaders | L | 35-28 |
| NCAAF | 2022/09/24 17:30 | Capital Crusaders v Wilmington Quakers | L | 31-34 |
| NCAAF | 2022/09/17 23:00 | Muskingum Muskies v Capital Crusaders | L | 37-7 |
| NCAAF | 2022/11/12 18:00 | Denison Big Red v Kenyon Lords | W | 49-12 |
| NCAAF | 2022/11/05 17:00 | Wooster Scots v Denison Big Red | W | 14-28 |
| NCAAF | 2022/10/22 16:00 | Wittenberg Tigers v Denison Big Red | W | 10-28 |
| NCAAF | 2022/10/15 19:00 | Denison Big Red v Hiram Terriers | W | 41-38 |
| NCAAF | 2022/10/08 18:00 | Ohio Wesleyan Battling Bishops v Denison Big Red | L | 41-7 |
| NCAAF | 2022/10/01 23:00 | Denison Big Red v Depauw Tigers | L | 13-17 |
| NCAAF | 2022/09/24 18:00 | Wabash Little Giants v Denison Big Red | W | 42-45 |
| NCAAF | 2022/09/17 17:00 | Denison Big Red v Oberlin Yeomen | W | 51-10 |