Stadium: Bison Stadium Round: 1
| NCAAF | 2022/10/22 18:00 | Case Western Reserve Spartans v Bethany Bison | L | 45-7 |
| NCAAF | 2021/10/16 18:00 | Case Western Reserve Spartans v Bethany Bison | L | 53-0 |
| NCAAF | 2019/11/02 18:00 | Case Western Reserve Spartans v Bethany Bison | L | 35-14 |
| NCAAF | 2018/10/27 18:00 | Bethany Bison v Case Western Reserve Spartans | L | 3-34 |
| NCAAF | 2023/09/23 17:00 | Allegheny Gators v Bethany Bison | L | 31-20 |
| NCAAF | 2023/09/16 17:00 | Thiel Tomcats v Bethany Bison | L | 22-14 |
| NCAAF | 2023/09/09 17:00 | Bethany Bison v Washington And Jefferson Presidents | L | 7-42 |
| NCAAF | 2022/11/12 18:00 | St Vincent Bearcats v Bethany Bison | L | 36-7 |
| NCAAF | 2022/11/05 17:00 | Bethany Bison v Allegheny Gators | L | 17-20 |
| NCAAF | 2022/10/29 23:00 | Geneva Golden Tornadoes v Bethany Bison | L | 34-6 |
| NCAAF | 2022/10/22 18:00 | Case Western Reserve Spartans v Bethany Bison | L | 45-7 |
| NCAAF | 2022/10/15 17:00 | Bethany Bison v Waynesburg Yellow Jackets | L | 17-34 |
| NCAAF | 2023/09/23 23:00 | Case Western Reserve Spartans v Geneva Golden Tornadoes | W | 42-7 |
| NCAAF | 2023/09/16 23:00 | Case Western Reserve Spartans v Grove City Wolverines | L | 24-27 |
| NCAAF | 2023/09/02 23:00 | Thiel Tomcats v Case Western Reserve Spartans | W | 0-14 |
| NCAAF | 2022/11/12 19:00 | Case Western Reserve Spartans v Carnegie Mellon Tartans | L | 7-20 |
| NCAAF | 2022/11/05 17:00 | Westminster Titans v Case Western Reserve Spartans | L | 14-13 |
| NCAAF | 2022/10/29 17:00 | Allegheny Gators v Case Western Reserve Spartans | W | 7-54 |
| NCAAF | 2022/10/22 18:00 | Case Western Reserve Spartans v Bethany Bison | W | 45-7 |
| NCAAF | 2022/10/08 17:00 | Case Western Reserve Spartans v St Vincent Bearcats | W | 45-21 |