Stadium: Blackstock Stadium Round: 1
| NCAAF | 2022/10/01 23:00 | Denison Big Red v Depauw Tigers | W | 13-17 |
| NCAAF | 2021/10/30 17:00 | Depauw Tigers v Denison Big Red | W | 27-10 |
| NCAAF | 2019/11/02 22:00 | Denison Big Red v Depauw Tigers | L | 42-7 |
| NCAAF | 2018/10/13 17:00 | Depauw Tigers v Denison Big Red | L | 12-20 |
| NCAAF | 2023/09/30 17:00 | Oberlin Yeomen v Depauw Tigers | W | 7-66 |
| NCAAF | 2023/09/23 17:00 | Depauw Tigers v Ohio Wesleyan Battling Bishops | W | 28-7 |
| NCAAF | 2023/09/16 17:00 | Depauw Tigers v Hiram Terriers | W | 49-0 |
| NCAAF | 2023/09/09 17:00 | Depauw Tigers v Anderson Ravens | W | 68-19 |
| NCAAF | 2023/09/02 23:00 | Rose Hulman Engineers v Depauw Tigers | W | 21-33 |
| NCAAF | 2022/11/19 17:00 | Carnegie Mellon Tartans v Depauw Tigers | L | 45-14 |
| NCAAF | 2022/11/12 18:07 | Depauw Tigers v Wabash Little Giants | W | 49-14 |
| NCAAF | 2022/11/05 17:00 | Depauw Tigers v Oberlin Yeomen | W | 72-0 |
| NCAAF | 2023/09/30 18:00 | Denison Big Red v Wittenberg Tigers | L | 24-27 |
| NCAAF | 2023/09/23 16:00 | Hiram Terriers v Denison Big Red | W | 24-55 |
| NCAAF | 2023/09/16 17:00 | Oberlin Yeomen v Denison Big Red | W | 0-70 |
| NCAAF | 2023/09/09 23:00 | Denison Big Red v Linfield Wildcats | L | 14-28 |
| NCAAF | 2023/09/02 17:30 | Capital Crusaders v Denison Big Red | W | 35-45 |
| NCAAF | 2022/11/12 18:00 | Denison Big Red v Kenyon Lords | W | 49-12 |
| NCAAF | 2022/11/05 17:00 | Wooster Scots v Denison Big Red | W | 14-28 |
| NCAAF | 2022/10/22 16:00 | Wittenberg Tigers v Denison Big Red | W | 10-28 |