Head to Head
| NFL | 2017/12/10 18:00 | SF 49ers v HOU Texans | W | 26-16 |
| NFL Preseason | 2016/08/14 23:00 | SF 49ers v HOU Texans | L | 13-24 |
Home History
| NFL Preseason | 2018/08/10 02:00 | DAL Cowboys v SF 49ers | W | 21-24 |
| NFL | 2017/12/31 21:25 | SF 49ers v LA Rams | W | 34-13 |
| NFL | 2017/12/24 21:05 | JAX Jaguars v SF 49ers | W | 33-44 |
| NFL | 2017/12/17 21:25 | TEN Titans v SF 49ers | W | 23-25 |
| NFL | 2017/12/10 18:00 | SF 49ers v HOU Texans | W | 26-16 |
| NFL | 2017/12/03 18:00 | SF 49ers v CHI Bears | W | 15-14 |
| NFL | 2017/11/26 21:05 | SEA Seahawks v SF 49ers | L | 24-13 |
| NFL | 2017/11/12 21:25 | NY Giants v SF 49ers | W | 21-31 |
Away History
| NFL Preseason | 2018/08/10 00:30 | HOU Texans v KC Chiefs | W | 17-10 |
| NFL | 2017/12/31 18:00 | HOU Texans v IND Colts | L | 13-22 |
| NFL | 2017/12/25 21:30 | PIT Steelers v HOU Texans | L | 34-6 |
| NFL | 2017/12/17 18:00 | HOU Texans v JAX Jaguars | L | 7-45 |
| NFL | 2017/12/10 18:00 | SF 49ers v HOU Texans | L | 26-16 |
| NFL | 2017/12/03 18:00 | HOU Texans v TEN Titans | L | 13-24 |
| NFL | 2017/11/28 01:30 | HOU Texans v BAL Ravens | L | 16-23 |
| NFL | 2017/11/19 18:00 | ARZ Cardinals v HOU Texans | W | 21-31 |