Stadium: Edwards-Maurer Field Round: 1
| NCAAF | 2022/10/08 17:00 | Depauw Tigers v Wittenberg Tigers | W | 7-30 |
| NCAAF | 2021/10/09 18:00 | Wittenberg Tigers v Depauw Tigers | L | 14-17 |
| NCAAF | 2019/09/28 17:00 | Depauw Tigers v Wittenberg Tigers | W | 10-17 |
| NCAAF | 2018/10/20 17:00 | Wittenberg Tigers v Depauw Tigers | W | 38-23 |
| NCAAF | 2023/10/14 20:00 | Oberlin Yeomen v Wittenberg Tigers | W | 7-72 |
| NCAAF | 2023/10/07 17:00 | Wittenberg Tigers v Hiram Terriers | W | 21-7 |
| NCAAF | 2023/09/30 18:00 | Denison Big Red v Wittenberg Tigers | W | 24-27 |
| NCAAF | 2023/09/23 16:00 | Wittenberg Tigers v Alma College Scots | L | 28-48 |
| NCAAF | 2023/09/16 22:00 | Wittenberg Tigers v Kenyon Lords | W | 56-17 |
| NCAAF | 2023/09/02 18:00 | Dubuque Spartans v Wittenberg Tigers | W | 27-28 |
| NCAAF | 2022/11/12 18:00 | Wittenberg Tigers v Hilbert Hawks | W | 56-8 |
| NCAAF | 2022/11/05 17:00 | Wittenberg Tigers v Ohio Wesleyan Battling Bishops | L | 7-14 |
| NCAAF | 2023/10/14 18:00 | Wooster Scots v Depauw Tigers | W | 7-53 |
| NCAAF | 2023/10/07 17:00 | Depauw Tigers v Denison Big Red | W | 17-6 |
| NCAAF | 2023/09/30 17:00 | Oberlin Yeomen v Depauw Tigers | W | 7-66 |
| NCAAF | 2023/09/23 17:00 | Depauw Tigers v Ohio Wesleyan Battling Bishops | W | 28-7 |
| NCAAF | 2023/09/16 17:00 | Depauw Tigers v Hiram Terriers | W | 49-0 |
| NCAAF | 2023/09/09 17:00 | Depauw Tigers v Anderson Ravens | W | 68-19 |
| NCAAF | 2023/09/02 23:00 | Rose Hulman Engineers v Depauw Tigers | W | 21-33 |
| NCAAF | 2022/11/19 17:00 | Carnegie Mellon Tartans v Depauw Tigers | L | 45-14 |