Head to Head
| NCAAF | 2015/10/30 23:00 | Wake Forest v Louisville | L | 19-20 |
| NCAAF | 2014/09/27 19:30 | Louisville v Wake Forest | L | 20-10 |
| NCAAF Bowl Games | 2007/01/02 12:00 | Louisville v Wake Forest | L | 24-13 |
Home History
| NCAAF | 2016/11/05 19:00 | Virginia v Wake Forest | W | 20-27 |
| NCAAF | 2016/10/29 19:30 | Army v Wake Forest | L | 21-13 |
| NCAAF | 2016/10/15 19:30 | Wake Forest v Florida State | L | 6-17 |
| NCAAF | 2016/10/08 23:00 | Syracuse v Wake Forest | W | 9-28 |
| NCAAF | 2016/10/01 19:30 | Wake Forest v NC State | L | 16-33 |
| NCAAF | 2016/09/24 19:30 | Wake Forest v Indiana | W | 33-28 |
| NCAAF | 2016/09/17 22:30 | Wake Forest v Delaware | W | 38-21 |
| NCAAF | 2016/09/10 19:30 | Duke v Wake Forest | W | 14-24 |
Away History
| NCAAF | 2016/11/05 16:00 | Louisville v Boston College | W | 52-7 |
| NCAAF | 2016/10/29 16:00 | Louisville v Virginia | W | 32-25 |
| NCAAF | 2016/10/22 16:00 | NC State v Louisville | W | 13-54 |
| NCAAF | 2016/10/14 23:00 | Duke v Louisville | W | 14-24 |
| NCAAF | 2016/10/02 00:00 | Louisville v Clemson | L | 36-42 |
| NCAAF | 2016/09/25 00:00 | Louisville v Marshall | W | 59-28 |
| NCAAF | 2016/09/17 16:00 | Florida State v Louisville | W | 20-63 |
| NCAAF | 2016/09/10 00:00 | Louisville v Syracuse | W | 62-28 |