Head to Head
| NCAAF | 2015/10/03 20:00 | SMU v East Carolina | L | 23-49 |
| NCAAF | 2014/10/04 16:00 | East Carolina v SMU | L | 45-24 |
| NCAAF | 2010/11/26 12:00 | East Carolina v SMU | W | 38-45 |
| NCAAF | 2009/10/10 12:00 | SMU v East Carolina | W | 28-21 |
| NCAAF | 2006/10/21 12:00 | East Carolina v SMU | L | 38-21 |
| NCAAF | 2005/10/15 12:00 | SMU v East Carolina | L | 17-24 |
Home History
| NCAAF | 2016/11/05 20:00 | Memphis v SMU | L | 51-7 |
| NCAAF | 2016/10/29 20:00 | SMU v Tulane | W | 35-31 |
| NCAAF | 2016/10/22 23:00 | Houston v SMU | W | 16-38 |
| NCAAF | 2016/10/08 00:00 | SMU v Tulsa | L | 40-43 |
| NCAAF | 2016/10/01 16:00 | SMU v Temple | L | 20-45 |
| NCAAF | 2016/09/24 00:00 | TCU v SMU | L | 33-3 |
| NCAAF | 2016/09/17 23:00 | SMU v Liberty | W | 29-14 |
| NCAAF | 2016/09/10 19:30 | SMU v Baylor | L | 13-40 |
Away History
| NCAAF | 2016/11/06 00:00 | East Carolina v Tulsa | L | 24-45 |
| NCAAF | 2016/10/29 16:00 | Connecticut v East Carolina | W | 3-41 |
| NCAAF | 2016/10/22 23:00 | East Carolina v Cincinnati | L | 19-31 |
| NCAAF | 2016/10/08 16:00 | South Florida v East Carolina | L | 38-22 |
| NCAAF | 2016/10/01 16:00 | Central Florida v East Carolina | L | 47-29 |
| NCAAF | 2016/09/24 16:30 | East Carolina v Virginia Tech | L | 17-54 |
| NCAAF | 2016/09/17 20:00 | South Carolina v East Carolina | L | 20-15 |
| NCAAF | 2016/09/10 16:00 | East Carolina v NC State | W | 33-30 |