| Uruguay Reserve League | 2023/04/17 12:30 | Boston River Reserves v Defensor Sporting Reserves | D | 1-1 |
| Uruguay Reserve League | 2022/09/27 13:00 | Defensor Sporting Reserves v Boston River Reserves | L | 2-3 |
| Uruguay Reserve League | 2022/03/29 19:00 | Boston River Reserves v Defensor Sporting Reserves | D | 1-1 |
| Uruguay Reserve League | 2020/11/03 18:00 | Boston River Reserves v Defensor Sporting Reserves | L | 2-1 |
| Uruguay Reserve League | 2019/11/11 19:00 | Boston River Reserves v Defensor Sporting Reserves | D | 1-1 |
| Uruguay Reserve League | 2019/04/07 16:15 | Defensor Sporting Reserves v Boston River Reserves | D | 0-0 |
| Uruguay Reserve League | 2018/05/02 18:00 | Defensor Sporting Reserves v Boston River Reserves | W | 3-2 |
| Uruguay Reserve League | 2017/11/20 13:00 | Boston River Reserves v Defensor Sporting Reserves | W | 0-2 |
| Uruguay Reserve League | 2024/04/08 14:00 | Racing Club de Montevideo Reserves v Defensor Sporting Reserves | L | 1-0 |
| Uruguay Reserve League | 2024/03/28 14:00 | Defensor Sporting Reserves v Juventud De Las Piedras Reserves | W | 2-0 |
| Uruguay Reserve League | 2024/03/25 19:00 | Atletico Fenix Reserves v Defensor Sporting Reserves | D | 0-0 |
| Uruguay Reserve League | 2023/11/27 19:00 | Nacional de Montevideo Reserves v Defensor Sporting Reserves | D | 1-1 |
| Uruguay Reserve League | 2023/11/13 12:00 | Defensor Sporting Reserves v La Luz Reserves | W | 4-2 |
| Uruguay Reserve League | 2023/10/31 12:00 | Montevideo Wanderers Reserves v Defensor Sporting Reserves | W | 1-2 |
| Uruguay Reserve League | 2023/10/23 12:00 | Defensor Sporting Reserves v Torque Reserves | W | 4-2 |
| Uruguay Reserve League | 2023/10/16 13:00 | Deportivo Maldonado Reserves v Defensor Sporting Reserves | L | 3-1 |
| Uruguay Reserve League | 2024/04/08 19:00 | Boston River Reserves v Liverpool Montevideo Reserves | L | 0-2 |
| Uruguay Reserve League | 2024/04/01 19:00 | Nacional de Montevideo Reserves v Boston River Reserves | L | 1-0 |
| Uruguay Reserve League | 2024/03/25 19:00 | Boston River Reserves v Albion FC Reserves | W | 1-0 |
| Uruguay Reserve League | 2024/03/11 19:30 | Atletico River Plate Reserves v Boston River Reserves | W | 0-1 |
| Uruguay Reserve League | 2023/11/27 19:00 | Penarol Reserves v Boston River Reserves | L | 1-0 |
| Uruguay Reserve League | 2023/11/13 13:00 | Boston River Reserves v Atletico Fenix Reserves | W | 2-0 |
| Uruguay Reserve League | 2023/11/06 19:00 | Boston River Reserves v Racing Club de Montevideo Reserves | D | 1-1 |
| Uruguay Reserve League | 2023/10/30 19:00 | Atletico River Plate Reserves v Boston River Reserves | W | 0-1 |