Head to Head
| NFL | 2020/12/08 01:15 | BUF Bills v SF 49ers | W | 34-24 |
| NFL | 2016/10/16 17:00 | SF 49ers v BUF Bills | W | 16-45 |
Home History
| NFL | 2024/09/13 00:15 | BUF Bills v MIA Dolphins | W | 31-10 |
| XFL | 2024/09/10 10:06 | BUF Bills v CHI Bears | D | 0-0 |
| NFL | 2024/09/08 17:00 | ARZ Cardinals v BUF Bills | W | 28-34 |
| NFL Preseason | 2024/08/24 17:00 | CAR Panthers v BUF Bills | L | 31-26 |
| NFL Preseason | 2024/08/17 23:00 | BUF Bills v PIT Steelers | W | 9-3 |
| NFL Preseason | 2024/08/10 17:00 | CHI Bears v BUF Bills | L | 33-6 |
| NFL | 2024/01/21 23:30 | KC Chiefs v BUF Bills | L | 27-24 |
| NFL | 2024/01/15 21:30 | PIT Steelers v BUF Bills | W | 17-31 |
Away History
| NFL | 2024/09/15 17:00 | SF 49ers v MIN Vikings | L | 17-23 |
| NFL | 2024/09/10 00:15 | NY Jets v SF 49ers | W | 19-32 |
| NFL Preseason | 2024/08/24 02:00 | SF 49ers v LV Raiders | D | 24-24 |
| NFL Preseason | 2024/08/19 00:00 | NO Saints v SF 49ers | W | 10-16 |
| NFL Preseason | 2024/08/10 23:00 | SF 49ers v TEN Titans | L | 13-17 |
| NFL | 2024/02/11 23:30 | SF 49ers v KC Chiefs | L | 22-25 |
| NFL | 2024/01/28 23:30 | DET Lions v SF 49ers | W | 31-34 |
| NFL | 2024/01/21 01:15 | GB Packers v SF 49ers | W | 21-24 |