Head to Head
| NFL Preseason | 2023/08/12 17:00 | IND Colts v BUF Bills | W | 19-23 |
| NFL Preseason | 2022/08/13 20:00 | IND Colts v BUF Bills | W | 24-27 |
| NFL | 2021/11/21 18:00 | IND Colts v BUF Bills | L | 41-15 |
| NFL | 2021/01/09 18:05 | IND Colts v BUF Bills | W | 24-27 |
| NFL Preseason | 2019/08/08 23:00 | IND Colts v BUF Bills | W | 16-24 |
| NFL | 2018/10/21 17:00 | BUF Bills v IND Colts | L | 5-37 |
| NFL | 2017/12/10 18:00 | IND Colts v BUF Bills | W | 7-13 |
| NFL Preseason | 2016/08/13 23:00 | BUF Bills v IND Colts | L | 18-19 |
Home History
| NFL | 2024/11/03 18:00 | MIA Dolphins v BUF Bills | W | 27-30 |
| NFL | 2024/10/27 20:05 | BUF Bills v SEA Seahawks | W | 31-10 |
| NFL | 2024/10/20 17:00 | TEN Titans v BUF Bills | W | 10-34 |
| NFL | 2024/10/15 00:15 | BUF Bills v NY Jets | W | 23-20 |
| NFL | 2024/10/06 17:00 | BUF Bills v HOU Texans | L | 20-23 |
| NFL | 2024/09/30 00:20 | BUF Bills v BAL Ravens | L | 10-35 |
| NFL | 2024/09/23 23:30 | JAX Jaguars v BUF Bills | W | 10-47 |
| NFL | 2024/09/13 00:15 | BUF Bills v MIA Dolphins | W | 31-10 |
Away History
| NFL | 2024/11/04 01:20 | IND Colts v MIN Vikings | L | 13-21 |
| NFL | 2024/10/27 17:00 | IND Colts v HOU Texans | L | 20-23 |
| NFL | 2024/10/20 17:00 | MIA Dolphins v IND Colts | W | 10-16 |
| NFL | 2024/10/13 17:00 | IND Colts v TEN Titans | W | 20-17 |
| NFL | 2024/10/06 17:00 | IND Colts v JAX Jaguars | L | 34-37 |
| NFL | 2024/09/29 17:00 | PIT Steelers v IND Colts | W | 24-27 |
| NFL | 2024/09/22 17:00 | CHI Bears v IND Colts | W | 16-21 |
| NFL | 2024/09/15 17:00 | IND Colts v GB Packers | L | 10-16 |