[5] BUF Sabres 5-4 PIT Penguins [29] 2018-11-20 00:00
Stadium: PPG Paints Arena Round: 1
Home Manager: Mike Sullivan Away Manager: Phil Housley
Head to Head
| NHL Pre-Season | 2018/09/26 23:00 | BUF Sabres v PIT Penguins | L | 1-5 |
| NHL Pre-Season | 2018/09/18 23:00 | PIT Penguins v BUF Sabres | W | 2-3 |
| NHL | 2017/12/03 00:00 | BUF Sabres v PIT Penguins | L | 1-5 |
| NHL | 2017/12/02 00:00 | PIT Penguins v BUF Sabres | L | 4-0 |
| NHL | 2017/11/15 00:00 | BUF Sabres v PIT Penguins | L | 4-5 |
| NHL Pre-Season | 2017/09/27 23:00 | BUF Sabres v PIT Penguins | L | 4-5 |
| NHL Pre-Season | 2017/09/19 23:00 | PIT Penguins v BUF Sabres | W | 3-4 |
| NHL | 2017/03/21 23:00 | PIT Penguins v BUF Sabres | L | 3-1 |
Home History
| NHL | 2018/11/17 23:00 | BUF Sabres v MIN Wild | W | 3-2 |
| NHL | 2018/11/17 01:00 | BUF Sabres v WIN Jets | W | 2-1 |
| NHL | 2018/11/14 00:30 | TB Lightning v BUF Sabres | W | 1-2 |
| NHL | 2018/11/10 18:00 | VAN Canucks v BUF Sabres | W | 3-4 |
| NHL | 2018/11/09 00:30 | BUF Sabres v MON Canadiens | W | 6-5 |
| NHL | 2018/11/05 00:00 | BUF Sabres v NY Rangers | L | 1-3 |
| NHL | 2018/11/03 18:00 | OTT Senators v BUF Sabres | W | 2-9 |
| NHL | 2018/11/01 23:30 | BUF Sabres v OTT Senators | L | 2-4 |
Away History
| NHL | 2018/11/18 00:00 | PIT Penguins v OTT Senators | L | 4-6 |
| NHL | 2018/11/16 00:00 | TB Lightning v PIT Penguins | L | 4-3 |
| NHL | 2018/11/14 00:00 | PIT Penguins v NJ Devils | L | 2-4 |
| NHL | 2018/11/11 00:00 | ARZ Coyotes v PIT Penguins | W | 0-4 |
| NHL | 2018/11/08 00:30 | PIT Penguins v WAS Capitals | L | 1-2 |
| NHL | 2018/11/06 00:00 | NJ Devils v PIT Penguins | L | 5-1 |
| NHL | 2018/11/03 23:00 | TOR Maple Leafs v PIT Penguins | L | 5-0 |
| NHL | 2018/11/01 23:00 | PIT Penguins v NY Islanders | L | 2-3 |