Stadium: William B. Greene Jr. Stadium Round: 1
Home Manager: Tre Lamb Away Manager: Chris Hatcher
| NCAAF | 2023/09/30 17:00 | East Tennessee State v Samford | W | 28-42 |
| NCAAF | 2022/10/22 19:30 | Samford v East Tennessee State | W | 55-45 |
| NCAAF | 2021/09/25 19:00 | East Tennessee State v Samford | L | 55-48 |
| NCAAF | 2021/02/20 18:00 | Samford v East Tennessee State | L | 17-24 |
| NCAAF | 2019/10/26 17:00 | East Tennessee State v Samford | W | 17-24 |
| NCAAF FCS | 2018/11/17 18:00 | Samford v East Tennessee State | W | 38-27 |
| NCAAF | 2017/11/11 20:00 | Samford v East Tennessee State | W | 42-7 |
| NCAAF | 2024/10/05 19:00 | VMI v Samford | W | 3-27 |
| NCAAF | 2024/09/14 23:00 | Alabama State v Samford | W | 7-12 |
| NCAAF | 2024/09/07 23:00 | Samford v Florida | L | 7-45 |
| NCAAF | 2024/08/31 22:00 | Samford v West Georgia | L | 29-38 |
| NCAAF | 2023/11/18 18:00 | Tennessee Martin v Samford | W | 17-27 |
| NCAAF | 2023/11/11 20:00 | Samford v Mercer | L | 21-28 |
| NCAAF | 2023/10/28 19:00 | The Citadel v Samford | W | 7-37 |
| NCAAF | 2023/10/21 17:30 | Samford v VMI | W | 27-14 |
| NCAAF | 2024/10/05 19:30 | Tennessee Chattanooga v East Tennessee State | L | 17-10 |
| NCAAF | 2024/09/28 21:00 | East Tennessee State v The Citadel | W | 34-17 |
| NCAAF | 2024/09/21 22:00 | East Tennessee State v Elon | W | 34-14 |
| NCAAF | 2024/09/14 21:30 | North Dakota State v East Tennessee State | L | 38-35 |
| NCAAF | 2024/09/07 21:30 | East Tennessee State v Virginia Wise Highland Cavaliers | W | 61-0 |
| NCAAF | 2024/08/31 19:30 | East Tennessee State v Appalachian St | L | 10-38 |
| NCAAF | 2023/11/18 18:00 | The Citadel v East Tennessee State | W | 23-35 |
| NCAAF | 2023/11/11 18:00 | East Tennessee State v Western Carolina | L | 7-58 |