Head to Head
| England Premier League 2 | 2024/04/29 11:00 | Southampton U21 v Man Utd U21 | W | 3-6 |
| England Premier League 2 | 2016/08/22 18:00 | Southampton U21 v Man Utd U21 | L | 2-0 |
Home History
| Premier League International Cup | 2024/12/07 12:00 | Man Utd U21 v Sparta Prague U21 | L | 1-3 |
| England National League Cup | 2024/12/03 19:00 | Rochdale v Man Utd U21 | W | 0-1 |
| England Premier League 2 | 2024/11/29 19:00 | Man Utd U21 v West Ham U21 | W | 1-0 |
| England National League Cup | 2024/11/19 19:30 | Altrincham v Man Utd U21 | W | 0-4 |
| England EFL Trophy | 2024/11/12 19:45 | Huddersfield v Man Utd U21 | L | 4-1 |
| England Premier League 2 | 2024/11/02 12:00 | Sunderland U21 v Man Utd U21 | L | 5-2 |
| Premier League International Cup | 2024/10/30 19:00 | Man Utd U21 v PSV U21 | D | 1-1 |
| England Premier League 2 | 2024/10/26 11:00 | Newcastle U21 v Man Utd U21 | W | 0-2 |
Away History
| Premier League International Cup | 2024/12/10 19:00 | Southampton U21 v Real Sociedad U21 | L | 3-4 |
| England National League Cup | 2024/12/03 19:00 | Aldershot v Southampton U21 | L | 2-1 |
| England Premier League 2 | 2024/11/29 14:00 | Stoke U21 v Southampton U21 | W | 0-3 |
| England U21 Premier League Cup | 2024/11/22 19:00 | Southampton U21 v West Brom U21 | D | 2-2 |
| England National League Cup | 2024/11/12 19:00 | Wealdstone v Southampton U21 | L | 3-1 |
| England U21 Premier League Cup | 2024/11/08 19:00 | Swansea U21 v Southampton U21 | W | 1-2 |
| England National League Cup | 2024/11/05 19:00 | Woking v Southampton U21 | L | 7-2 |
| England Premier League 2 | 2024/11/01 19:00 | Southampton U21 v Brighton U21 | L | 2-4 |