Head to Head
| England Premier League 2 | 2023/12/15 11:30 | Southampton U21 v Derby U21 | L | 2-1 |
| England Premier League 2 | 2023/03/31 18:00 | Derby U21 v Southampton U21 | L | 1-3 |
| England Premier League 2 | 2023/01/06 19:00 | Southampton U21 v Derby U21 | L | 3-0 |
| England U21 Premier League Cup | 2015/03/05 19:00 | Southampton U21 v Derby U21 | L | 4-2 |
Home History
| England Premier League 2 | 2025/02/10 19:00 | Nottm Forest U21 v Derby U21 | D | 1-1 |
| England U21 Premier League Cup | 2025/01/31 19:00 | Chelsea U21 v Derby U21 | L | 2-1 |
| England Premier League 2 | 2025/01/27 19:00 | Derby U21 v Blackburn U21 | D | 0-0 |
| England U21 Premier League Cup | 2025/01/24 19:00 | Bournemouth U21 v Derby U21 | W | 0-3 |
| England Premier League 2 | 2025/01/17 19:00 | Reading U21 v Derby U21 | W | 0-1 |
| England National League Cup | 2025/01/14 19:00 | Woking v Derby U21 | L | 2-0 |
| England Premier League 2 | 2025/01/10 19:00 | Derby U21 v Tottenham U21 | W | 2-1 |
| England Premier League 2 | 2024/12/13 19:00 | Fulham U21 v Derby U21 | L | 4-0 |
Away History
| England Premier League 2 | 2025/02/14 13:00 | Everton U21 v Southampton U21 | W | 1-2 |
| England National League Cup | 2025/02/11 19:45 | Maidenhead Utd v Southampton U21 | W | 0-6 |
| England Premier League 2 | 2025/02/07 19:00 | Southampton U21 v Liverpool U21 | D | 1-1 |
| England U21 Premier League Cup | 2025/02/04 19:00 | Fleetwood Town U21 v Southampton U21 | L | 2-0 |
| England U21 Premier League Cup | 2025/01/31 19:00 | Southampton U21 v Swansea U21 | D | 2-2 |
| England Premier League 2 | 2025/01/24 19:00 | Chelsea U21 v Southampton U21 | W | 0-2 |
| Premier League International Cup | 2025/01/21 19:00 | Southampton U21 v Anderlecht Reserves | W | 3-1 |
| England Premier League 2 | 2025/01/17 12:00 | Southampton U21 v Newcastle U21 | W | 4-2 |