Head to Head
| England Premier League 2 | 2023/12/15 11:30 | Southampton U21 v Derby U21 | L | 2-1 |
| England Premier League 2 | 2023/03/31 18:00 | Derby U21 v Southampton U21 | L | 1-3 |
| England Premier League 2 | 2023/01/06 19:00 | Southampton U21 v Derby U21 | L | 3-0 |
| England U21 Premier League Cup | 2015/03/05 19:00 | Southampton U21 v Derby U21 | L | 4-2 |
Home History
| England Premier League 2 | 2025/01/10 19:00 | Derby U21 v Tottenham U21 | W | 2-1 |
| England Premier League 2 | 2024/12/13 19:00 | Fulham U21 v Derby U21 | L | 4-0 |
| England U21 Premier League Cup | 2024/12/06 19:00 | Derby U21 v Brentford U21 | L | 1-4 |
| England National League Cup | 2024/12/03 19:00 | Wealdstone v Derby U21 | L | 2-0 |
| England Premier League 2 | 2024/11/29 19:00 | Derby U21 v Chelsea U21 | L | 2-6 |
| England U21 Premier League Cup | 2024/11/08 19:00 | Derby U21 v Chelsea U21 | W | 4-3 |
| England National League Cup | 2024/11/05 19:30 | Maidenhead Utd v Derby U21 | L | 10-9 |
| England Premier League 2 | 2024/11/01 19:00 | Derby U21 v West Brom U21 | W | 4-1 |
Away History
| England Premier League 2 | 2025/01/10 19:00 | Southampton U21 v Fulham U21 | W | 5-0 |
| Premier League International Cup | 2024/12/19 19:00 | Southampton U21 v Sporting U21 | L | 0-5 |
| England Premier League 2 | 2024/12/14 12:00 | Man Utd U21 v Southampton U21 | L | 5-1 |
| Premier League International Cup | 2024/12/10 19:00 | Southampton U21 v Real Sociedad U21 | L | 3-4 |
| England National League Cup | 2024/12/03 19:00 | Aldershot v Southampton U21 | L | 2-1 |
| England Premier League 2 | 2024/11/29 14:00 | Stoke U21 v Southampton U21 | W | 0-3 |
| England U21 Premier League Cup | 2024/11/22 19:00 | Southampton U21 v West Brom U21 | D | 2-2 |
| England National League Cup | 2024/11/12 19:00 | Wealdstone v Southampton U21 | L | 3-1 |