[2] Southend 3-0 Southampton U21 [4] 2018-11-14 19:45
Weather: Cold Stadium: Roots Hall Pitch: Excellent Round: 3
Home History
| England FA Cup | 2018/11/10 15:00 | Southend v Crawley Town | D | 1-1 |
| England League 1 | 2018/11/03 15:00 | Barnsley v Southend | L | 1-0 |
| England League 1 | 2018/10/27 14:00 | Sunderland v Southend | L | 3-0 |
| England League 1 | 2018/10/23 18:45 | Southend v Walsall | W | 3-0 |
| England League 1 | 2018/10/20 14:00 | Southend v Coventry | L | 1-2 |
| England League 1 | 2018/10/13 14:00 | Gillingham v Southend | W | 0-2 |
| England EFL Trophy | 2018/10/09 18:45 | Colchester v Southend | L | 2-0 |
| England League 1 | 2018/10/06 14:00 | Southend v Oxford Utd | D | 0-0 |
Away History
| England EFL Trophy | 2018/10/09 18:00 | Cambridge Utd v Southampton U21 | L | 4-0 |
| England EFL Trophy | 2018/09/04 18:45 | Colchester v Southampton U21 | W | 0-2 |
| England EFL Trophy | 2017/11/07 19:45 | Northampton v Southampton U21 | L | 7-5 |
| England EFL Trophy | 2017/10/03 18:00 | Cambridge Utd v Southampton U21 | W | 0-1 |
| England EFL Trophy | 2017/08/29 18:45 | Peterborough v Southampton U21 | L | 2-0 |
| England Premier League 2 | 2017/08/14 18:00 | Southampton U21 v Reading U21 | W | 4-0 |
| England Premier League 2 | 2016/09/19 18:00 | Southampton U21 v Leicester U21 | D | 2-2 |
| England EFL Trophy | 2016/08/30 18:45 | Charlton v Southampton U21 | L | 5-4 |