Stadium: Spratt Memorial Stadium Round: 1
| NCAAF | 2023/11/11 20:00 | Missouri Southern Lions v Missouri Western Griffons | L | 47-41 |
| NCAAF | 2022/10/29 18:00 | Missouri Western Griffons v Missouri Southern Lions | W | 31-27 |
| NCAAF | 2021/10/30 19:00 | Missouri Southern Lions v Missouri Western Griffons | W | 28-45 |
| NCAAF | 2019/10/12 21:00 | Missouri Western Griffons v Missouri Southern Lions | W | 43-34 |
| NCAAF | 2018/10/06 19:00 | Missouri Southern Lions v Missouri Western Griffons | W | 10-33 |
| NCAAF | 2024/09/08 00:00 | Fort Hays State University Tigers v Missouri Western Griffons | L | 30-16 |
| NCAAF | 2024/08/29 23:00 | Northeastern State Riverhawks v Missouri Western Griffons | W | 31-33 |
| NCAAF | 2023/11/11 20:00 | Missouri Southern Lions v Missouri Western Griffons | L | 47-41 |
| NCAAF | 2023/11/04 18:00 | Missouri Western Griffons v Pittsburgh State Gorillas | W | 31-30 |
| NCAAF | 2023/10/28 18:00 | Missouri Western Griffons v Northeastern State Riverhawks | W | 44-0 |
| NCAAF | 2023/10/21 17:00 | Nebraska Kearney v Missouri Western Griffons | W | 17-20 |
| NCAAF | 2023/10/14 18:00 | Missouri Western Griffons v NW Missouri State | L | 23-27 |
| NCAAF | 2023/10/07 20:00 | Washburn Ichabods Football v Missouri Western Griffons | W | 21-61 |
| NCAAF | 2024/09/08 00:00 | Missouri Southern Lions v Pittsburgh State Gorillas | L | 17-42 |
| NCAAF | 2024/08/30 00:00 | Midwestern State University Mustangs v Missouri Southern Lions | L | 18-11 |
| NCAAF | 2023/11/11 20:00 | Missouri Southern Lions v Missouri Western Griffons | W | 47-41 |
| NCAAF | 2023/11/04 18:00 | Emporia State v Missouri Southern Lions | L | 63-28 |
| NCAAF | 2023/10/28 19:00 | Missouri Southern Lions v Central Missouri Mules | L | 21-42 |
| NCAAF | 2023/10/21 19:00 | Blue Tigers v Missouri Southern Lions | W | 5-63 |
| NCAAF | 2023/10/14 19:00 | Missouri Southern Lions v Pittsburgh State Gorillas | L | 21-31 |
| NCAAF | 2023/10/07 19:00 | Missouri Southern Lions v Fort Hays State University Tigers | L | 22-35 |