[2] Novak Djokovic 6-1,6-1 Kei Nishikori [5] 2016-11-19 20:00
Ground: Hardcourt indoor
Head to Head
| ATP Madrid | 2016/05/07 18:20 | Novak Djokovic v Kei Nishikori | 6-3,7-6 |
| ATP Miami | 2016/04/03 17:00 | Novak Djokovic v Kei Nishikori | 6-3,6-3 |
| US Open | 2014/09/06 16:00 | Novak Djokovic v Kei Nishikori | 4-6,6-1,6-7,3-6 |
Home History
| ATP World Tour Finals | 2016/11/17 14:00 | Novak Djokovic v David Goffin | 6-1,6-2 |
| ATP World Tour Finals | 2016/11/15 20:00 | Novak Djokovic v Milos Raonic | 7-6,7-6 |
| ATP World Tour Finals | 2016/11/13 14:00 | Novak Djokovic v Dominic Thiem | 6-7,6-0,6-2 |
| ATP Paris | 2016/11/04 15:40 | Novak Djokovic v Marin Cilic | 4-6,6-7 |
| ATP Paris | 2016/11/03 14:45 | Novak Djokovic v Grigor Dimitrov | 4-6,6-2,6-3 |
| ATP Paris | 2016/11/02 15:50 | Novak Djokovic v Gilles Muller | 6-3,6-4 |
| ATP Shanghai | 2016/10/15 08:30 | Novak Djokovic v Roberto Bautista-Agut | 4-6,4-6 |
| ATP Shanghai | 2016/10/14 07:05 | Novak Djokovic v Mischa Zverev | 3-6,7-6,6-3 |
Away History
| ATP World Tour Finals | 2016/11/18 20:00 | Kei Nishikori v Marin Cilic | 6-3,2-6,3-6 |
| ATP World Tour Finals | 2016/11/16 14:00 | Andy Murray v Kei Nishikori | 6-7,6-4,6-4 |
| ATP World Tour Finals | 2016/11/14 14:00 | Stan Wawrinka v Kei Nishikori | 2-6,3-6 |
| ATP Paris | 2016/11/03 19:10 | Kei Nishikori v Jo-Wilfried Tsonga | 6-0,3-6,6-7 |
| ATP Paris | 2016/11/02 10:00 | Kei Nishikori v Viktor Troicki | 6-2,7-5 |
| ATP Basel | 2016/10/30 13:30 | Marin Cilic v Kei Nishikori | 6-1,7-6 |
| ATP Basel | 2016/10/29 12:30 | Kei Nishikori v Gilles Muller | 4-6,7-6,6-3 |
| ATP Basel | 2016/10/28 16:00 | Juan Martin Del Potro v Kei Nishikori | 5-7,4-6 |