Stadium: Lewis C. Everett Stadium Round: 1
| NCAAF | 2023/10/28 17:00 | Guilford Quakers v Hampden Sydney Tigers | W | 21-42 |
| NCAAF | 2022/10/29 17:00 | Hampden Sydney Tigers v Guilford Quakers | W | 28-21 |
| NCAAF | 2021/09/25 17:00 | Guilford Quakers v Hampden Sydney Tigers | W | 27-28 |
| NCAAF | 2019/10/26 17:00 | Guilford Quakers v Hampden Sydney Tigers | L | 37-27 |
| NCAAF | 2018/10/20 17:00 | Hampden Sydney Tigers v Guilford Quakers | W | 38-35 |
| NCAAF | 2024/09/21 17:00 | Hampden Sydney Tigers v Centre Colonels | W | 38-34 |
| NCAAF | 2024/09/14 17:00 | Brevard Tornados v Hampden Sydney Tigers | W | 30-51 |
| NCAAF | 2024/09/07 17:00 | Hampden Sydney Tigers v Delaware Valley Aggies | L | 21-41 |
| NCAAF | 2023/11/11 18:00 | Randolph Macon Yellow Jackets v Hampden Sydney Tigers | L | 49-10 |
| NCAAF | 2023/11/04 17:00 | Hampden Sydney Tigers v Shenandoah Hornets | W | 26-25 |
| NCAAF | 2023/10/28 17:00 | Guilford Quakers v Hampden Sydney Tigers | W | 21-42 |
| NCAAF | 2023/10/21 17:00 | Hampden Sydney Tigers v Washington And Lee Generals | L | 17-21 |
| NCAAF | 2023/10/14 20:00 | Averett Cougars v Hampden Sydney Tigers | W | 28-31 |
| NCAAF | 2024/09/21 17:00 | Guilford Quakers v Sewanee Tigers | W | 44-35 |
| NCAAF | 2024/09/14 23:00 | Guilford Quakers v Methodist Monarchs | W | 14-12 |
| NCAAF | 2024/09/07 16:00 | Greensboro Pride v Guilford Quakers | W | 0-14 |
| NCAAF | 2023/11/11 19:00 | Bridgewater Eagles v Guilford Quakers | L | 47-15 |
| NCAAF | 2023/11/04 19:00 | Guilford Quakers v Averett Cougars | L | 13-34 |
| NCAAF | 2023/10/28 17:00 | Guilford Quakers v Hampden Sydney Tigers | L | 21-42 |
| NCAAF | 2023/10/21 19:30 | Ferrum Panthers v Guilford Quakers | L | 28-0 |
| NCAAF | 2023/10/14 17:00 | Guilford Quakers v Shenandoah Hornets | L | 20-31 |