[25] CAL Flames 2-4 BUF Sabres [27] 2016-11-22 00:00
Stadium: First Niagara Center Round: 1
Home History
| NHL | 2016/11/21 00:30 | CAL Flames v DET Red Wings | W | 3-2 |
| NHL | 2016/11/19 02:00 | CHI Blackhawks v CAL Flames | L | 3-2 |
| NHL | 2016/11/17 03:00 | ARZ Coyotes v CAL Flames | W | 1-2 |
| NHL | 2016/11/16 01:00 | CAL Flames v MIN Wild | W | 1-0 |
| NHL | 2016/11/13 03:00 | NY Rangers v CAL Flames | L | 4-1 |
| NHL | 2016/11/11 02:00 | DAL Stars v CAL Flames | L | 4-2 |
| NHL | 2016/11/07 02:30 | CAL Flames v ANA Ducks | L | 1-4 |
| NHL | 2016/11/06 02:00 | CAL Flames v LA Kings | L | 0-5 |
Away History
| NHL | 2016/11/20 00:00 | PIT Penguins v BUF Sabres | W | 1-2 |
| NHL | 2016/11/18 00:00 | TB Lightning v BUF Sabres | L | 4-1 |
| NHL | 2016/11/16 01:00 | BUF Sabres v STL Blues | L | 1-4 |
| NHL | 2016/11/13 00:00 | BUF Sabres v NJ Devils | L | 2-4 |
| NHL | 2016/11/12 00:00 | NJ Devils v BUF Sabres | L | 2-1 |
| NHL | 2016/11/10 00:30 | OTT Senators v BUF Sabres | L | 2-1 |
| NHL | 2016/11/08 00:00 | BUF Sabres v BOS Bruins | L | 0-4 |
| NHL | 2016/11/05 23:00 | BUF Sabres v OTT Senators | W | 2-1 |