Stadium: Williams Stadium Round: 1
| NCAAF | 2023/09/16 19:00 | Otterbein Cardinals v Wilmington Quakers | W | 21-47 |
| NCAAF | 2022/09/17 18:00 | Wilmington Quakers v Otterbein Cardinals | W | 32-26 |
| NCAAF | 2021/11/13 18:30 | Otterbein Cardinals v Wilmington Quakers | W | 33-37 |
| NCAAF | 2019/11/16 18:30 | Otterbein Cardinals v Wilmington Quakers | W | 27-28 |
| NCAAF | 2018/11/10 18:30 | Wilmington Quakers v Otterbein Cardinals | L | 24-34 |
| NCAAF | 2024/10/12 17:30 | Mount Union v Wilmington Quakers | L | 78-19 |
| NCAAF | 2024/09/28 17:30 | Ohio Northern Polar Bears v Wilmington Quakers | L | 59-3 |
| NCAAF | 2024/09/21 19:00 | Wilmington Quakers v Muskingum Muskies | L | 13-42 |
| NCAAF | 2024/09/14 17:30 | Wilmington Quakers v Baldwin Wallace Yellow Jackets | L | 7-42 |
| NCAAF | 2024/09/07 18:00 | Wooster Scots v Wilmington Quakers | L | 56-13 |
| NCAAF | 2023/11/11 19:00 | Wilmington Quakers v Ohio Northern Polar Bears | L | 14-38 |
| NCAAF | 2023/11/04 17:30 | Muskingum Muskies v Wilmington Quakers | L | 64-63 |
| NCAAF | 2023/10/28 17:30 | Heidelberg Student Princes v Wilmington Quakers | L | 49-35 |
| NCAAF | 2024/10/12 17:30 | Baldwin Wallace Yellow Jackets v Otterbein Cardinals | L | 36-7 |
| NCAAF | 2024/10/05 16:30 | Otterbein Cardinals v Mount Union | L | 0-21 |
| NCAAF | 2024/09/21 18:00 | Otterbein Cardinals v Marietta Pioneers | L | 14-51 |
| NCAAF | 2024/09/14 16:00 | Muskingum Muskies v Otterbein Cardinals | L | 24-7 |
| NCAAF | 2024/09/07 22:00 | Ohio Wesleyan Battling Bishops v Otterbein Cardinals | L | 26-7 |
| NCAAF | 2023/11/11 18:30 | Otterbein Cardinals v John Carroll Blue Streaks | L | 22-37 |
| NCAAF | 2023/11/04 17:30 | Ohio Northern Polar Bears v Otterbein Cardinals | L | 49-6 |
| NCAAF | 2023/10/28 17:30 | Mount Union v Otterbein Cardinals | L | 51-14 |