Stadium: William H. Greene Stadium Round: 1
| NCAAF | 2023/10/28 18:00 | Missouri S&t Miners v William Jewell College Cardinals | L | 57-20 |
| NCAAF | 2022/10/15 18:00 | William Jewell College Cardinals v Missouri S&t Miners | L | 14-41 |
| NCAAF | 2021/10/16 18:00 | Missouri S&t Miners v William Jewell College Cardinals | L | 37-16 |
| NCAAF | 2019/09/28 22:00 | William Jewell College Cardinals v Missouri S&t Miners | L | 24-41 |
| NCAAF | 2018/10/13 18:00 | Missouri S&t Miners v William Jewell College Cardinals | L | 59-21 |
| NCAAF | 2024/10/12 18:00 | Upper Iowa v William Jewell College Cardinals | L | 38-31 |
| NCAAF | 2024/10/05 18:00 | William Jewell College Cardinals v Indianapolis Greyhounds | L | 20-23 |
| NCAAF | 2024/09/28 18:00 | William Jewell College Cardinals v Davenport Panthers | L | 7-17 |
| NCAAF | 2024/09/21 17:00 | Blue Tigers v William Jewell College Cardinals | W | 20-48 |
| NCAAF | 2024/09/14 23:00 | Kentucky Wesleyan v William Jewell College Cardinals | W | 16-23 |
| NCAAF | 2024/08/31 20:00 | Fort Lewis Skyhawks v William Jewell College Cardinals | W | 20-35 |
| NCAAF | 2023/11/11 19:00 | McKendree v William Jewell College Cardinals | L | 35-14 |
| NCAAF | 2023/11/04 17:00 | William Jewell College Cardinals v Southwest Baptist University Bearcats | L | 3-71 |
| NCAAF | 2024/10/12 23:00 | Truman Bulldogs v Missouri S&t Miners | L | 48-17 |
| NCAAF | 2024/10/05 23:00 | Missouri S&t Miners v Southwest Baptist University Bearcats | W | 65-24 |
| NCAAF | 2024/09/21 23:00 | Missouri S&t Miners v Quincy | L | 14-21 |
| NCAAF | 2024/09/14 23:00 | Missouri S&t Miners v Lincoln Oaklanders | W | 45-6 |
| NCAAF | 2024/09/07 23:00 | Delta State v Missouri S&t Miners | L | 55-18 |
| NCAAF | 2024/08/29 23:00 | Wayne State Wildcats v Missouri S&t Miners | L | 49-17 |
| NCAAF | 2023/11/11 19:00 | Missouri S&t Miners v Truman Bulldogs | L | 14-24 |
| NCAAF | 2023/11/04 18:00 | Quincy v Missouri S&t Miners | W | 14-21 |