Stadium: Blackstock Stadium Round: 1
| NCAAF | 2023/10/21 18:00 | Wittenberg Tigers v Depauw Tigers | W | 35-41 |
| NCAAF | 2022/10/08 17:00 | Depauw Tigers v Wittenberg Tigers | L | 7-30 |
| NCAAF | 2021/10/09 18:00 | Wittenberg Tigers v Depauw Tigers | W | 14-17 |
| NCAAF | 2019/09/28 17:00 | Depauw Tigers v Wittenberg Tigers | L | 10-17 |
| NCAAF | 2018/10/20 17:00 | Wittenberg Tigers v Depauw Tigers | L | 38-23 |
| NCAAF | 2024/10/19 18:00 | Denison Big Red v Depauw Tigers | W | 34-53 |
| NCAAF | 2024/10/05 18:00 | Ohio Wesleyan Battling Bishops v Depauw Tigers | W | 14-53 |
| NCAAF | 2024/09/28 16:00 | Depauw Tigers v Oberlin Yeomen | W | 72-0 |
| NCAAF | 2024/09/21 17:00 | Depauw Tigers v Wooster Scots | W | 51-14 |
| NCAAF | 2024/09/14 17:00 | Berry Vikings v Depauw Tigers | W | 0-33 |
| NCAAF | 2024/09/07 17:00 | Depauw Tigers v Rose Hulman Engineers | W | 57-14 |
| NCAAF | 2023/11/18 17:00 | Alma College Scots v Depauw Tigers | L | 32-17 |
| NCAAF | 2023/11/11 18:07 | Wabash Little Giants v Depauw Tigers | W | 30-33 |
| NCAAF | 2024/10/19 17:00 | Kenyon Lords v Wittenberg Tigers | W | 7-27 |
| NCAAF | 2024/10/12 23:00 | Wittenberg Tigers v Ohio Wesleyan Battling Bishops | W | 17-6 |
| NCAAF | 2024/10/05 18:00 | Wittenberg Tigers v Denison Big Red | L | 20-30 |
| NCAAF | 2024/09/28 17:00 | Wittenberg Tigers v Howard Payne Yellow Jackets | W | 36-29 |
| NCAAF | 2024/09/07 16:00 | Baldwin Wallace Yellow Jackets v Wittenberg Tigers | L | 24-14 |
| NCAAF | 2023/11/11 18:00 | Wittenberg Tigers v Wooster Scots | W | 52-24 |
| NCAAF | 2023/11/04 20:00 | Ohio Wesleyan Battling Bishops v Wittenberg Tigers | W | 28-36 |
| NCAAF | 2023/10/28 17:00 | Wabash Little Giants v Wittenberg Tigers | L | 52-20 |