Stadium: Carl Smith Stadium Round: 1
| NCAAF | 2023/10/28 17:00 | Mars Hill Lions v Virginia Wise Highland Cavaliers | L | 49-18 |
| NCAAF | 2022/10/29 16:00 | Virginia Wise Highland Cavaliers v Mars Hill Lions | L | 16-20 |
| NCAAF | 2021/09/18 17:00 | Mars Hill Lions v Virginia Wise Highland Cavaliers | L | 44-9 |
| NCAAF | 2019/09/21 16:00 | Virginia Wise Highland Cavaliers v Mars Hill Lions | L | 14-21 |
| NCAAF | 2024/10/19 17:00 | Carson–Newman Eagles v Virginia Wise Highland Cavaliers | L | 35-23 |
| NCAAF | 2024/10/12 18:00 | Virginia Wise Highland Cavaliers v Anderson Trojans | L | 13-20 |
| NCAAF | 2024/10/05 18:00 | Virginia Wise Highland Cavaliers v Wingate Bulldogs | L | 0-33 |
| NCAAF | 2024/09/21 18:00 | Virginia Wise Highland Cavaliers v Catawba College | W | 31-28 |
| NCAAF | 2024/09/14 19:00 | Concord University Mountain Lions v Virginia Wise Highland Cavaliers | W | 0-28 |
| NCAAF | 2024/09/07 21:30 | East Tennessee State v Virginia Wise Highland Cavaliers | L | 61-0 |
| NCAAF | 2023/11/11 17:00 | Virginia Wise Highland Cavaliers v Wingate Bulldogs | L | 0-27 |
| NCAAF | 2023/11/04 16:00 | Virginia Wise Highland Cavaliers v Carson–Newman Eagles | L | 7-52 |
| NCAAF | 2024/10/19 18:30 | Mars Hill Lions v Tusculum Pioneers | W | 30-3 |
| NCAAF | 2024/10/12 17:00 | Mars Hill Lions v Carson–Newman Eagles | L | 27-28 |
| NCAAF | 2024/10/05 17:00 | Newberry Wolves v Mars Hill Lions | W | 9-34 |
| NCAAF | 2024/09/21 17:00 | Mars Hill Lions v Lenoir Rhyne Bears | L | 21-29 |
| NCAAF | 2024/08/29 23:00 | Mars Hill Lions v Delta State | L | 16-47 |
| NCAAF | 2023/11/11 18:00 | Mars Hill Lions v Newberry Wolves | W | 21-14 |
| NCAAF | 2023/11/04 17:00 | Tusculum Pioneers v Mars Hill Lions | L | 29-27 |
| NCAAF | 2023/10/28 17:00 | Mars Hill Lions v Virginia Wise Highland Cavaliers | W | 49-18 |