[26] Serena Williams 6-1,6-2 Venus Williams [16] 2018-09-01 00:00
Stadium: Arthur Ashe Stadium Round: 25 Ground: Hardcourt outdoor
Head to Head
| WTA Indian Wells | 2018/03/13 02:10 | Venus Williams v Serena Williams | 6-3,6-4 |
| Australian Open 2017 Women | 2017/01/28 08:30 | Venus Williams v Serena Williams | 4-6,4-6 |
| Wimbledon Women | 2015/07/06 12:00 | Serena Williams v Venus Williams | 6-4,6-3 |
| WTA Montreal | 2014/08/09 17:00 | Serena Williams v Venus Williams | 7-6,2-6,3-6 |
Home History
| US Open Women | 2018/08/29 23:05 | Serena Williams v Carina Witthoeft | 6-2,6-2 |
| US Open Women | 2018/08/28 00:00 | Serena Williams v Magda Linette | 6-4,6-0 |
| WTA Cincinnati | 2018/08/15 00:30 | Petra Kvitova v Serena Williams | 6-3,2-6,6-3 |
| WTA Cincinnati | 2018/08/13 23:00 | Daria Saville v Serena Williams | 1-6,2-6 |
| WTA San Jose | 2018/08/01 02:00 | Serena Williams v Johanna Konta | 1-6,0-6 |
| Wimbledon Women | 2018/07/14 15:10 | Angelique Kerber v Serena Williams | 6-3,6-3 |
| Wimbledon Women | 2018/07/12 13:25 | Julia Goerges v Serena Williams | 2-6,4-6 |
| Wimbledon Women | 2018/07/10 13:45 | Serena Williams v Camila Giorgi | 3-6,6-3,6-4 |
Away History
| US Open Women | 2018/08/29 17:00 | Camila Giorgi v Venus Williams | 4-6,5-7 |
| US Open Women | 2018/08/27 18:45 | Svetlana Kuznetsova v Venus Williams | 3-6,7-5,3-6 |
| WTA Montreal | 2018/08/10 00:40 | Simona Halep v Venus Williams | 6-2,6-2 |
| WTA Montreal | 2018/08/09 17:45 | Sorana Cirstea v Venus Williams | 6-7,4-6 |
| WTA Montreal | 2018/08/06 19:30 | Caroline Dolehide v Venus Williams | 5-7,1-6 |
| WTA San Jose | 2018/08/04 02:00 | Venus Williams v Maria Sakkari | 4-6,6-7 |
| WTA San Jose | 2018/08/03 02:00 | Venus Williams v Heather Watson | 6-4,4-6,6-0 |
| Wimbledon Women | 2018/07/06 13:15 | Kiki Bertens v Venus Williams | 6-2,6-7,8-6 |