Charleston Southern 58-7 Mississippi Valley State 2017-09-30 22:00
Stadium: Buccaneer Field Round: 1
Home History
| NCAAF | 2017/09/23 22:00 | Charleston Southern v Point University Skyhawks | W | 66-0 |
| NCAAF | 2017/09/16 22:00 | Elon v Charleston Southern | L | 19-17 |
| NCAAF | 2017/09/02 20:00 | Charleston Southern v Mississippi State | L | 0-49 |
| NCAAF | 2016/09/10 16:30 | Florida State v Charleston Southern | L | 52-8 |
| NCAAF | 2016/08/27 23:30 | North Dakota State v Charleston Southern | L | 24-17 |
| NCAAF | 2015/12/12 01:00 | Jacksonville State v Charleston Southern | L | 58-38 |
| NCAAF | 2015/12/05 18:00 | Charleston Southern v The Citadel | W | 14-6 |
| NCAAF | 2015/11/21 21:00 | Alabama v Charleston Southern | L | 56-6 |
Away History
| NCAAF | 2017/09/23 23:00 | Mississippi Valley State v Grambling State | L | 6-38 |
| NCAAF | 2017/09/09 23:00 | SO Illinois v Mississippi Valley State | L | 55-3 |
| NCAAF | 2017/09/02 19:30 | North Dakota State v Mississippi Valley State | L | 72-7 |
| NCAAF | 2016/09/02 22:00 | Eastern Michigan v Mississippi Valley State | L | 61-14 |
| NCAAF | 2015/09/06 00:00 | New Mexico v Mississippi Valley State | L | 66-0 |
| NCAAF | 2009/09/05 12:00 | Arkansas State v Mississippi Valley State | L | 61-0 |
| NCAAF | 2000/08/26 12:00 | Louisiana Tech v Mississippi Valley State | L | 63-10 |