| Uruguay Reserve League | 2024/05/13 18:00 | Defensor Sporting Reserves v Danubio Reserves | D | 1-1 |
| Uruguay Reserve League | 2023/05/15 13:00 | Danubio Reserves v Defensor Sporting Reserves | W | 3-1 |
| Uruguay Reserve League | 2022/12/01 19:00 | Defensor Sporting Reserves v Danubio Reserves | W | 0-5 |
| Uruguay Reserve League | 2022/05/31 18:00 | Danubio Reserves v Defensor Sporting Reserves | L | 0-3 |
| Uruguay Reserve League | 2019/11/07 19:00 | Defensor Sporting Reserves v Danubio Reserves | L | 3-1 |
| Uruguay Reserve League | 2019/04/16 18:00 | Danubio Reserves v Defensor Sporting Reserves | L | 2-5 |
| Uruguay Reserve League | 2018/08/01 18:00 | Defensor Sporting Reserves v Danubio Reserves | W | 0-3 |
| Uruguay Reserve League | 2024/10/22 18:00 | Liverpool Montevideo Reserves v Danubio Reserves | L | 4-0 |
| Uruguay Reserve League | 2024/10/15 12:00 | Danubio Reserves v Nacional de Montevideo Reserves | L | 0-3 |
| Uruguay Reserve League | 2024/10/10 12:00 | Danubio Reserves v Atletico River Plate Reserves | L | 0-1 |
| Uruguay Reserve League | 2024/10/07 18:00 | Albion FC Reserves v Danubio Reserves | W | 1-2 |
| Uruguay Reserve League | 2024/09/30 18:00 | Danubio Reserves v Atletico River Plate Reserves | D | 0-0 |
| Uruguay Reserve League | 2024/09/23 18:00 | Penarol Reserves v Danubio Reserves | L | 4-0 |
| Uruguay Reserve League | 2024/08/26 18:00 | Deportivo Maldonado Reserves v Danubio Reserves | D | 1-1 |
| Uruguay Reserve League | 2024/08/12 18:00 | Danubio Reserves v Montevideo Wanderers Reserves | D | 0-0 |
| Uruguay Reserve League | 2024/10/22 18:00 | Defensor Sporting Reserves v Deportivo Maldonado Reserves | W | 2-0 |
| Uruguay Reserve League | 2024/10/14 18:00 | Progreso Reserves v Defensor Sporting Reserves | D | 1-1 |
| Uruguay Reserve League | 2024/10/07 12:30 | Defensor Sporting Reserves v Miramar Misiones Reserves | L | 0-1 |
| Uruguay Reserve League | 2024/09/30 14:17 | Boston River Reserves v Defensor Sporting Reserves | W | 0-3 |
| Uruguay Reserve League | 2024/09/23 12:30 | Defensor Sporting Reserves v Racing Club de Montevideo Reserves | L | 0-1 |
| Uruguay Reserve League | 2024/09/16 13:00 | Juventud De Las Piedras Reserves v Defensor Sporting Reserves | D | 0-0 |
| Uruguay Reserve League | 2024/09/09 13:00 | Defensor Sporting Reserves v Atletico Fenix Reserves | L | 1-3 |
| Uruguay Reserve League | 2024/08/26 13:00 | Defensor Sporting Reserves v Torque Reserves | W | 1-0 |