[26] DET Red Wings 2-1 BUF Sabres [25] 2016-11-24 00:00
Stadium: First Niagara Center Round: 1
Home History
| NHL | 2016/11/21 00:30 | CAL Flames v DET Red Wings | L | 3-2 |
| NHL | 2016/11/19 00:00 | DET Red Wings v WAS Capitals | L | 0-1 |
| NHL | 2016/11/16 00:30 | TB Lightning v DET Red Wings | L | 4-3 |
| NHL | 2016/11/13 00:00 | DET Red Wings v MON Canadiens | L | 0-5 |
| NHL | 2016/11/11 00:30 | VAN Canucks v DET Red Wings | W | 1-3 |
| NHL | 2016/11/09 00:00 | DET Red Wings v PHI Flyers | W | 3-2 |
| NHL | 2016/11/06 21:50 | EDM Oilers v DET Red Wings | L | 2-1 |
| NHL | 2016/11/04 23:30 | WIN Jets v DET Red Wings | L | 5-3 |
Away History
| NHL | 2016/11/22 00:00 | CAL Flames v BUF Sabres | W | 2-4 |
| NHL | 2016/11/20 00:00 | PIT Penguins v BUF Sabres | W | 1-2 |
| NHL | 2016/11/18 00:00 | TB Lightning v BUF Sabres | L | 4-1 |
| NHL | 2016/11/16 01:00 | BUF Sabres v STL Blues | L | 1-4 |
| NHL | 2016/11/13 00:00 | BUF Sabres v NJ Devils | L | 2-4 |
| NHL | 2016/11/12 00:00 | NJ Devils v BUF Sabres | L | 2-1 |
| NHL | 2016/11/10 00:30 | OTT Senators v BUF Sabres | L | 2-1 |
| NHL | 2016/11/08 00:00 | BUF Sabres v BOS Bruins | L | 0-4 |