Head to Head
| Mexico Liga MX | 2024/07/21 01:00 | Santos Laguna v Tigres UANL | W | 0-3 |
| Mexico Liga MX | 2024/02/11 03:10 | Santos Laguna v Tigres UANL | W | 0-3 |
| Mexico Liga MX | 2023/08/31 03:00 | Tigres UANL v Santos Laguna | W | 3-2 |
| Mexico Liga MX | 2023/01/09 01:00 | Santos Laguna v Tigres UANL | W | 0-3 |
| Club Friendly List | 2022/12/27 23:00 | Tigres UANL v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2022/08/15 00:05 | Tigres UANL v Santos Laguna | W | 2-0 |
| Mexico Liga MX | 2022/01/13 02:06 | Santos Laguna v Tigres UANL | D | 1-1 |
| Mexico Liga MX | 2021/11/29 00:00 | Tigres UANL v Santos Laguna | W | 1-0 |
Home History
| Mexico Liga MX | 2025/01/11 23:00 | Atletico San Luis v Tigres UANL | W | 1-3 |
| Mexico Liga MX | 2024/12/02 01:00 | Tigres UANL v Atletico San Luis | D | 0-0 |
| Mexico Liga MX | 2024/11/29 01:00 | Atletico San Luis v Tigres UANL | L | 3-0 |
| Mexico Liga MX | 2024/11/10 03:05 | Cruz Azul v Tigres UANL | D | 1-1 |
| Mexico Liga MX | 2024/11/07 01:00 | Tigres UANL v Toluca | W | 2-1 |
| Mexico Liga MX | 2024/11/02 03:05 | Tijuana v Tigres UANL | W | 0-3 |
| Mexico Liga MX | 2024/10/27 03:00 | Tigres UANL v Pachuca | W | 2-1 |
| Mexico Liga MX | 2024/10/23 03:06 | Mazatlan FC v Tigres UANL | L | 2-0 |
Away History
| Mexico Liga MX | 2025/01/12 01:05 | Chivas Guadalajara v Santos Laguna | L | 1-0 |
| Mexico Liga MX | 2024/11/09 01:00 | Queretaro v Santos Laguna | L | 3-2 |
| Mexico Liga MX | 2024/11/06 01:00 | Santos Laguna v Chivas Guadalajara | L | 0-2 |
| Mexico Liga MX | 2024/11/03 03:10 | Cruz Azul v Santos Laguna | L | 2-0 |
| Mexico Liga MX | 2024/10/26 01:00 | Santos Laguna v Mazatlan FC | D | 0-0 |
| Mexico Liga MX | 2024/10/23 01:00 | Santos Laguna v Pachuca | D | 1-1 |
| Mexico Liga MX | 2024/10/20 01:05 | Club America v Santos Laguna | L | 3-0 |
| Mexico Liga MX | 2024/10/07 02:05 | Santos Laguna v Juarez FC | L | 0-2 |