Head to Head
| Mexico Liga MX Femenil | 2024/09/26 21:45 | Club America Women v Santos Laguna Women | L | 2-0 |
| Mexico Liga MX Femenil | 2024/01/23 01:06 | Santos Laguna Women v Club America Women | L | 0-5 |
| Mexico Liga MX Femenil | 2023/07/23 23:00 | Club America Women v Santos Laguna Women | L | 6-0 |
| Mexico Liga MX Femenil | 2023/02/09 23:05 | Santos Laguna Women v Club America Women | D | 1-1 |
| Mexico Liga MX Femenil | 2022/07/20 00:00 | Club America Women v Santos Laguna Women | L | 2-0 |
| Mexico Liga MX Femenil | 2022/04/12 00:00 | Santos Laguna Women v Club America Women | L | 0-3 |
| Mexico Liga MX Femenil | 2021/07/18 17:00 | Club America Women v Santos Laguna Women | L | 2-1 |
| Mexico Liga MX Femenil | 2021/04/06 00:00 | Santos Laguna Women v Club America Women | L | 1-2 |
Home History
| Mexico Liga MX Femenil | 2025/02/09 18:00 | Toluca Women v Santos Laguna Women | L | 2-1 |
| Mexico Liga MX Femenil | 2025/02/07 03:00 | Santos Laguna Women v Tijuana Women | L | 1-3 |
| Mexico Liga MX Femenil | 2025/02/01 01:00 | Atletico San Luis Women v Santos Laguna Women | L | 3-0 |
| Mexico Liga MX Femenil | 2025/01/28 03:00 | Santos Laguna Women v Juarez FC Women | L | 1-2 |
| Mexico Liga MX Femenil | 2025/01/22 03:00 | Santos Laguna Women v Club Necaxa Women | L | 2-3 |
| Mexico Liga MX Femenil | 2025/01/14 23:00 | Unam Pumas Women v Santos Laguna Women | L | 6-1 |
| Mexico Liga MX Femenil | 2025/01/10 23:00 | Santos Laguna Women v Chivas Guadalajara Women | L | 0-1 |
| Mexico Liga MX Femenil | 2025/01/04 01:00 | Atlas Women v Santos Laguna Women | W | 1-3 |
Away History
| Mexico Liga MX Femenil | 2025/02/11 02:00 | Club America Women v Monterrey Women | W | 3-2 |
| Mexico Liga MX Femenil | 2025/02/07 02:00 | Club America Women v Mazatlan FC Women | W | 6-0 |
| Mexico Liga MX Femenil | 2025/02/04 01:00 | Pachuca Women v Club America Women | L | 2-1 |
| Mexico Liga MX Femenil | 2025/01/25 21:45 | Club America Women v Leon Women | W | 5-0 |
| Mexico Liga MX Femenil | 2025/01/22 01:00 | Atlas Women v Club America Women | W | 0-3 |
| Mexico Liga MX Femenil | 2025/01/16 21:45 | Club Necaxa Women v Club America Women | W | 0-5 |
| Mexico Liga MX Femenil | 2025/01/10 23:00 | Club America Women v Queretaro Women | W | 7-0 |
| Mexico Liga MX Femenil | 2025/01/07 01:10 | Club America Women v Cruz Azul Women | W | 2-1 |