Head to Head
| World Club Friendlies | 2024/08/16 17:00 | Medeama SC v Asante Kotoko | W | 2-1 |
| Ghana Premier League | 2024/04/27 15:00 | Medeama SC v Asante Kotoko | D | 1-1 |
| Ghana Premier League | 2023/11/19 15:00 | Asante Kotoko v Medeama SC | L | 1-0 |
| Ghana Premier League | 2023/03/26 18:00 | Asante Kotoko v Medeama SC | W | 0-2 |
| Ghana Premier League | 2022/11/12 15:00 | Medeama SC v Asante Kotoko | L | 0-1 |
| Ghana Premier League | 2022/05/29 15:00 | Medeama SC v Asante Kotoko | L | 0-2 |
| Ghana Premier League | 2022/01/23 15:00 | Asante Kotoko v Medeama SC | L | 1-0 |
| Ghana Premier League | 2021/04/24 15:00 | Asante Kotoko v Medeama SC | W | 1-2 |
Home History
| Ghana Premier League | 2025/01/01 15:00 | Medeama SC v Karela United FC | W | 1-0 |
| Ghana Premier League | 2024/12/14 15:00 | Vision FC v Medeama SC | L | 3-2 |
| Ghana Premier League | 2024/11/24 15:00 | Young Apostles v Medeama SC | W | 0-2 |
| Ghana Premier League | 2024/11/17 15:00 | Medeama SC v Bibiani Gold Stars | W | 2-0 |
| Ghana Premier League | 2024/11/09 15:00 | Dreams v Medeama SC | L | 1-0 |
| Ghana Premier League | 2024/11/01 18:00 | Medeama SC v Hearts of Oak | L | 0-2 |
| Ghana Premier League | 2024/10/28 09:00 | Aduana Stars v Medeama SC | D | 2-2 |
| Ghana Premier League | 2024/10/20 15:00 | Medeama SC v Nations FC | W | 1-0 |
Away History
| Ghana Premier League | 2024/12/27 18:00 | Asante Kotoko v Bibiani Gold Stars | W | 2-0 |
| Ghana Premier League | 2024/12/21 15:00 | Dreams v Asante Kotoko | W | 1-2 |
| Ghana Premier League | 2024/12/15 15:00 | Asante Kotoko v Hearts of Oak | W | 1-0 |
| Ghana Premier League | 2024/11/24 15:00 | Aduana Stars v Asante Kotoko | W | 0-2 |
| Ghana Premier League | 2024/11/17 15:00 | Asante Kotoko v Nations FC | L | 0-2 |
| Ghana Premier League | 2024/11/10 15:00 | Bechem FC v Asante Kotoko | L | 1-0 |
| Ghana Premier League | 2024/11/03 15:00 | Asante Kotoko v Heart of Lions | L | 0-1 |
| Ghana Premier League | 2024/10/30 19:00 | Legon Cities FC v Asante Kotoko | L | 2-1 |