Head to Head
| Mexico U23 League | 2024/09/28 15:00 | Atletico San Luis U23 v Santos Laguna U23 | L | 3-1 |
| Mexico U23 League | 2024/04/28 17:30 | Santos Laguna U23 v Atletico San Luis U23 | L | 0-3 |
| Mexico U23 League | 2023/11/11 15:00 | Atletico San Luis U23 v Santos Laguna U23 | D | 2-2 |
Home History
| Mexico U23 League | 2025/01/25 17:00 | Santos Laguna U23 v Club America U23 | L | 1-4 |
| Mexico U23 League | 2025/01/20 15:30 | Pachuca U23 v Santos Laguna U23 | W | 2-4 |
| Mexico U23 League | 2025/01/11 15:03 | Chivas Guadalajara U23 v Santos Laguna U23 | W | 0-2 |
| Mexico U23 League | 2024/11/08 15:00 | Queretaro U23 v Santos Laguna U23 | L | 1-0 |
| Mexico U23 League | 2024/11/05 17:00 | Santos Laguna U23 v Chivas Guadalajara U23 | D | 2-2 |
| Mexico U23 League | 2024/11/02 15:00 | Cruz Azul U23 v Santos Laguna U23 | W | 0-2 |
| Mexico U23 League | 2024/10/25 17:00 | Santos Laguna U23 v Mazatlan FC U23 | W | 2-0 |
| Mexico U23 League | 2024/10/22 17:00 | Santos Laguna U23 v Pachuca U23 | L | 2-3 |
Away History
| Mexico U23 League | 2025/01/24 15:00 | Atletico San Luis U23 v Necaxa U23 | W | 1-0 |
| Mexico U23 League | 2025/01/17 15:00 | Puebla U23 v Atletico San Luis U23 | L | 1-0 |
| Mexico U23 League | 2025/01/11 15:00 | Atletico San Luis U23 v Tigres UANL U23 | W | 2-1 |
| Mexico U23 League | 2024/12/08 16:00 | Tigres UANL U23 v Atletico San Luis U23 | W | 1-3 |
| Mexico U23 League | 2024/12/06 01:05 | Atletico San Luis U23 v Tigres UANL U23 | L | 0-1 |
| Mexico U23 League | 2024/12/01 00:00 | Atletico San Luis U23 v Juarez FC U23 | D | 3-3 |
| Mexico U23 League | 2024/11/27 17:00 | Juarez FC U23 v Atletico San Luis U23 | D | 1-1 |
| Mexico U23 League | 2024/11/24 00:00 | Atletico San Luis U23 v Toluca U23 | D | 0-0 |