Head to Head
| Chile Primera Division | 2022/07/03 19:00 | La Serena v O'Higgins | L | 1-0 |
| Chile Primera Division | 2022/02/04 23:00 | O'Higgins v La Serena | W | 3-0 |
| Chile Primera Division | 2021/09/14 17:00 | La Serena v O'Higgins | L | 2-0 |
| Chile Primera Division | 2021/04/17 22:00 | O'Higgins v La Serena | D | 0-0 |
| Chile Primera Division | 2021/01/02 13:30 | O'Higgins v La Serena | D | 1-1 |
| Chile Primera Division | 2020/09/04 22:30 | La Serena v O'Higgins | D | 1-1 |
Home History
| Chile Cup | 2025/02/01 21:00 | Deportes Temuco v O'Higgins | D | 1-1 |
| Chile Cup | 2025/01/26 21:00 | O'Higgins v Rangers de Talca | W | 3-1 |
| America Friendlies | 2025/01/18 21:30 | O'Higgins v Club Deportes Santa Cruz | W | 1-0 |
| Chile Primera Division | 2024/11/10 15:00 | O'Higgins v Cobreloa | L | 0-3 |
| Chile Primera Division | 2024/11/02 21:00 | Cobresal v O'Higgins | L | 3-1 |
| Chile Primera Division | 2024/10/19 18:00 | O'Higgins v Nublense | L | 1-3 |
| Chile Primera Division | 2024/10/06 18:00 | O'Higgins v Universidad Catolica | L | 0-2 |
| Chile Primera Division | 2024/09/30 23:30 | Audax Italiano v O'Higgins | L | 2-0 |
Away History
| Chile Cup | 2025/02/02 15:00 | Coquimbo Unido v La Serena | D | 1-1 |
| Chile Cup | 2025/01/27 21:00 | Cobresal v La Serena | W | 1-2 |
| America Friendlies | 2025/01/18 21:00 | La Serena v Union Espanola | W | 1-0 |
| Chile Primera B | 2024/10/19 18:00 | La Serena v Deportes Temuco | W | 4-2 |
| Chile Primera B | 2024/10/13 18:00 | Rangers de Talca v La Serena | D | 1-1 |
| Chile Primera B | 2024/10/05 18:00 | Union San Felipe v La Serena | D | 0-0 |
| Chile Primera B | 2024/09/29 15:30 | La Serena v Deportes Recoleta | W | 1-0 |
| Chile Primera B | 2024/09/14 23:00 | San Marcos De Arica v La Serena | D | 1-1 |