Louisville 20-38 Boston College 2018-10-13 16:30
Stadium: Alumni Stadium Round: 1
Home Manager: Steve Addazio Away Manager: Bobby Petrino
Head to Head
| NCAAF | 2017/10/14 16:20 | Boston College v Louisville | L | 45-42 |
| NCAAF | 2016/11/05 16:00 | Louisville v Boston College | W | 52-7 |
| NCAAF | 2015/10/24 16:30 | Louisville v Boston College | W | 17-14 |
| NCAAF | 2014/11/09 00:15 | Boston College v Louisville | W | 19-38 |
Home History
| NCAAF | 2018/10/05 23:00 | Georgia Tech v Louisville | L | 66-31 |
| NCAAF | 2018/09/29 19:30 | Florida State v Louisville | L | 28-24 |
| NCAAF | 2018/09/22 16:30 | Louisville v Virginia | L | 3-27 |
| NCAAF | 2018/09/15 23:30 | Western Kentucky v Louisville | W | 17-20 |
| NCAAF | 2018/09/08 23:00 | Indiana State v Louisville | W | 7-31 |
| NCAAF | 2018/09/02 00:00 | Louisville v Alabama | L | 14-51 |
| NCAAF | 2017/12/30 17:00 | Louisville v Mississippi State | L | 27-31 |
| NCAAF | 2017/11/25 17:00 | Louisville v Kentucky | W | 44-17 |
Away History
| NCAAF | 2018/10/06 16:30 | Boston College v NC State | L | 23-28 |
| NCAAF | 2018/09/29 16:00 | Temple v Boston College | W | 35-45 |
| NCAAF | 2018/09/22 16:00 | Boston College v Purdue | L | 13-30 |
| NCAAF | 2018/09/13 21:30 | Boston College v Wake Forest | W | 41-34 |
| NCAAF | 2018/09/08 17:00 | Holy Cross v Boston College | W | 14-62 |
| NCAAF | 2018/09/01 17:00 | Massachusetts v Boston College | W | 21-55 |
| NCAAF | 2017/12/27 22:15 | Boston College v Iowa | L | 20-27 |
| NCAAF | 2017/11/25 17:20 | Boston College v Syracuse | W | 42-14 |