[28] BUF Sabres 5-4 OTT Senators [5] 2016-11-30 00:30
Stadium: Canadian Tire Centre Round: 1
Head to Head
| NHL | 2016/11/10 00:30 | OTT Senators v BUF Sabres | L | 2-1 |
| NHL | 2016/11/05 23:00 | BUF Sabres v OTT Senators | W | 2-1 |
Home History
| NHL | 2016/11/25 22:00 | BUF Sabres v WAS Capitals | L | 1-3 |
| NHL | 2016/11/24 00:00 | DET Red Wings v BUF Sabres | L | 2-1 |
| NHL | 2016/11/22 00:00 | CAL Flames v BUF Sabres | W | 2-4 |
| NHL | 2016/11/20 00:00 | PIT Penguins v BUF Sabres | W | 1-2 |
| NHL | 2016/11/18 00:00 | TB Lightning v BUF Sabres | L | 4-1 |
| NHL | 2016/11/16 01:00 | BUF Sabres v STL Blues | L | 1-4 |
| NHL | 2016/11/13 00:00 | BUF Sabres v NJ Devils | L | 2-4 |
| NHL | 2016/11/12 00:00 | NJ Devils v BUF Sabres | L | 2-1 |
Away History
| NHL | 2016/11/28 00:00 | OTT Senators v NY Rangers | W | 2-0 |
| NHL | 2016/11/27 00:00 | CAR Hurricanes v OTT Senators | W | 1-2 |
| NHL | 2016/11/25 00:30 | BOS Bruins v OTT Senators | W | 1-3 |
| NHL | 2016/11/23 00:30 | OTT Senators v MON Canadiens | W | 4-3 |
| NHL | 2016/11/20 00:00 | FLA Panthers v OTT Senators | L | 4-1 |
| NHL | 2016/11/18 00:30 | NAS Predators v OTT Senators | L | 5-1 |
| NHL | 2016/11/16 00:00 | OTT Senators v PHI Flyers | W | 3-2 |
| NHL | 2016/11/13 22:00 | MIN Wild v OTT Senators | L | 2-1 |