Stadium: Arthur J. Rooney Athletic Field Round: 1
Home Manager: Jerry Schmitt Away Manager: Mark Nofri
| NCAAF FCS | 2018/11/03 16:00 | Duquesne v Wagner | W | 47-30 |
| NCAAF | 2018/10/20 16:00 | St.Francis (PA) v Duquesne | W | 20-27 |
| NCAAF | 2018/10/13 23:00 | Robert Morris v Duquesne | W | 24-48 |
| NCAAF | 2018/10/06 17:00 | Bryant v Duquesne | L | 21-20 |
| NCAAF | 2018/09/23 04:00 | Duquesne v Hawaii | L | 21-42 |
| NCAAF | 2018/09/15 16:00 | Dayton v Duquesne | W | 26-31 |
| NCAAF | 2018/09/08 16:00 | Valparaiso v Duquesne | W | 21-23 |
| NCAAF | 2018/09/01 18:00 | Duquesne v Lock Haven | W | 45-0 |
| NCAAF | 2018/11/03 16:00 | Sacred Heart v Robert Morris | W | 38-7 |
| NCAAF | 2018/10/27 17:00 | Sacred Heart v Bryant | W | 49-26 |
| NCAAF | 2018/10/20 17:00 | Central Connecticut v Sacred Heart | W | 25-28 |
| NCAAF | 2018/10/13 22:00 | Sacred Heart v Dartmouth | L | 0-42 |
| NCAAF | 2018/10/06 19:00 | Pennsylvania v Sacred Heart | L | 31-27 |
| NCAAF | 2018/09/29 17:30 | Sacred Heart v Cornell Big Red | L | 24-43 |
| NCAAF | 2018/09/22 22:00 | Sacred Heart v Wagner | W | 41-14 |
| NCAAF | 2018/09/08 19:00 | Sacred Heart v Bucknell | W | 30-14 |