[21] FLA Panthers 3-4 BUF Sabres [12] 2019-01-04 00:00
Stadium: KeyBank Center Round: 1
Home Manager: Phil Housley Away Manager: Bob Boughner
Head to Head
| NHL | 2018/12/19 00:00 | FLA Panthers v BUF Sabres | W | 5-2 |
| NHL | 2018/12/01 00:00 | BUF Sabres v FLA Panthers | W | 2-3 |
| NHL | 2018/04/07 23:00 | BUF Sabres v FLA Panthers | W | 3-4 |
| NHL | 2018/03/03 00:30 | BUF Sabres v FLA Panthers | W | 1-4 |
| NHL | 2018/02/02 00:00 | FLA Panthers v BUF Sabres | W | 4-2 |
| NHL | 2017/11/11 00:00 | FLA Panthers v BUF Sabres | W | 4-1 |
| NHL | 2017/04/08 23:00 | BUF Sabres v FLA Panthers | W | 0-3 |
| NHL | 2017/03/27 23:00 | FLA Panthers v BUF Sabres | L | 2-4 |
Home History
| NHL | 2019/01/01 00:30 | FLA Panthers v DET Red Wings | W | 4-3 |
| NHL | 2018/12/30 00:00 | PHI Flyers v FLA Panthers | W | 1-2 |
| NHL | 2018/12/29 00:00 | MON Canadiens v FLA Panthers | L | 5-3 |
| NHL | 2018/12/24 00:00 | FLA Panthers v CHI Blackhawks | W | 6-3 |
| NHL | 2018/12/22 19:00 | FLA Panthers v DET Red Wings | W | 2-1 |
| NHL | 2018/12/21 00:00 | FLA Panthers v TOR Maple Leafs | L | 1-6 |
| NHL | 2018/12/19 00:00 | FLA Panthers v BUF Sabres | W | 5-2 |
| NHL | 2018/12/16 00:00 | TOR Maple Leafs v FLA Panthers | W | 3-4 |
Away History
| NHL | 2018/12/31 23:00 | NY Islanders v BUF Sabres | L | 3-1 |
| NHL | 2018/12/30 00:00 | BOS Bruins v BUF Sabres | L | 3-2 |
| NHL | 2018/12/28 01:00 | BUF Sabres v STL Blues | L | 1-4 |
| NHL | 2018/12/23 00:00 | ANA Ducks v BUF Sabres | W | 0-3 |
| NHL | 2018/12/22 00:00 | BUF Sabres v WAS Capitals | L | 1-2 |
| NHL | 2018/12/19 00:00 | FLA Panthers v BUF Sabres | L | 5-2 |
| NHL | 2018/12/16 22:00 | BUF Sabres v BOS Bruins | W | 4-2 |
| NHL | 2018/12/16 00:00 | BUF Sabres v WAS Capitals | L | 3-4 |