South Carolina 35-56 Clemson 2018-11-25 00:00
Stadium: Memorial Stadium Round: 1
Home Manager: Dabo Swinney Away Manager: Will Muschamp
Head to Head
| NCAAF | 2017/11/26 00:30 | Clemson v South Carolina | L | 34-10 |
| NCAAF | 2016/11/27 00:30 | South Carolina v Clemson | L | 7-56 |
| NCAAF | 2015/11/28 17:00 | South Carolina v Clemson | L | 32-37 |
| NCAAF | 2014/11/29 17:00 | Clemson v South Carolina | L | 35-17 |
| NCAAF | 2012/11/24 12:00 | Clemson v South Carolina | W | 17-27 |
| NCAAF | 2011/11/26 12:00 | South Carolina v Clemson | W | 34-13 |
| NCAAF | 2010/11/27 12:00 | Clemson v South Carolina | W | 7-29 |
| NCAAF | 2009/11/28 12:00 | South Carolina v Clemson | W | 34-17 |
| NCAAF | 2008/11/29 12:00 | Clemson v South Carolina | L | 31-14 |
| NCAAF | 2007/11/24 12:00 | South Carolina v Clemson | L | 21-23 |
| NCAAF | 2006/11/25 12:00 | Clemson v South Carolina | W | 28-31 |
| NCAAF | 2005/11/19 12:00 | South Carolina v Clemson | L | 9-13 |
| NCAAF | 2004/11/20 12:00 | Clemson v South Carolina | L | 29-7 |
| NCAAF | 2003/11/22 12:00 | South Carolina v Clemson | L | 17-63 |
| NCAAF | 2002/11/23 12:00 | Clemson v South Carolina | L | 27-20 |
| NCAAF | 2001/11/17 12:00 | South Carolina v Clemson | W | 20-15 |
| NCAAF | 2000/11/18 12:00 | Clemson v South Carolina | L | 16-14 |