Stadium: Jack Breslin Students Events Center Round: 1
Home Manager: Tom Izzo Away Manager: Chris Collins
| NCAAB | 2018/02/17 19:00 | Michigan State v Northwestern | L | 65-60 |
| NCAAB | 2016/12/30 23:00 | Northwestern v Michigan State | L | 52-61 |
| NCAAB | 2016/01/29 02:00 | Northwestern v Michigan State | L | 45-76 |
| NCAAB | 2015/02/11 00:00 | Northwestern v Michigan State | L | 44-68 |
| NCAAB | 2015/01/11 17:00 | Michigan State v Northwestern | L | 84-77 |
| NCAAB | 2014/03/14 12:00 | Michigan State v Northwestern | L | 67-51 |
| NCAAB | 2012/01/14 12:00 | Northwestern v Michigan State | W | 81-74 |
| NCAAB | 2011/01/15 12:00 | Michigan State v Northwestern | L | 71-67 |
| NCAAB | 2011/01/03 12:00 | Northwestern v Michigan State | L | 62-65 |
| NCAAB | 2010/01/30 12:00 | Michigan State v Northwestern | L | 79-70 |
| NCAAB | 2010/01/02 12:00 | Northwestern v Michigan State | L | 70-91 |
| NCAAB | 2009/01/21 12:00 | Michigan State v Northwestern | W | 63-70 |
| NCAAB | 2009/01/03 12:00 | Northwestern v Michigan State | L | 66-77 |
| NCAAB | 2008/02/09 12:00 | Michigan State v Northwestern | L | 70-55 |
| NCAAB | 2008/01/24 12:00 | Northwestern v Michigan State | L | 62-78 |
| NCAAB | 2007/03/08 12:00 | Northwestern v Michigan State | L | 57-62 |
| NCAAB | 2007/01/10 12:00 | Michigan State v Northwestern | L | 66-45 |
| NCAAB | 2006/02/04 12:00 | Northwestern v Michigan State | L | 66-77 |
| NCAAB | 2005/03/02 12:00 | Northwestern v Michigan State | L | 58-69 |
| NCAAB | 2005/01/08 12:00 | Michigan State v Northwestern | L | 87-58 |
| NCAAB | 2004/03/12 12:00 | Michigan State v Northwestern | L | 68-55 |
| NCAAB | 2004/02/21 12:00 | Michigan State v Northwestern | L | 66-56 |
| NCAAB | 2004/01/21 12:00 | Northwestern v Michigan State | L | 61-73 |
| NCAAB | 2003/02/15 12:00 | Michigan State v Northwestern | L | 64-51 |