[12] Cruz Azul 1-2 Santos Laguna [11] 2019-02-16 23:00
Stadium: Estadio Azul Round: 7
Referee: Eduardo Galvan Basulto Home Manager: Pedro Caixinha Away Manager: Salvador Reyes
Head to Head
| Mexico Liga MX | 2018/08/26 23:00 | Santos Laguna v Cruz Azul | D | 1-1 |
| Mexico Liga MX | 2018/02/26 00:00 | Santos Laguna v Cruz Azul | L | 2-0 |
| Mexico Liga MX | 2017/09/16 22:00 | Cruz Azul v Santos Laguna | W | 2-1 |
| Mexico Cup | 2017/03/15 01:00 | Santos Laguna v Cruz Azul | W | 1-3 |
| Mexico Liga MX | 2017/02/13 00:00 | Santos Laguna v Cruz Azul | D | 2-2 |
| Mexico Liga MX | 2016/08/20 22:00 | Cruz Azul v Santos Laguna | W | 3-1 |
| Mexico Liga MX | 2016/04/16 22:00 | Cruz Azul v Santos Laguna | L | 0-1 |
| Mexico Liga MX | 2015/10/24 02:30 | Santos Laguna v Cruz Azul | W | 1-2 |
| Mexico Liga MX | 2015/01/17 23:00 | Cruz Azul v Santos Laguna | W | 1-0 |
| Mexico Liga MX | 2014/07/26 02:30 | Santos Laguna v Cruz Azul | D | 1-1 |