[13] Santos Laguna 2-1 Queretaro [17] 2019-04-21 23:06
Stadium: Estadio TSM Corona Round: 15
Referee: Francisco Chacon Gutierrez Home Manager: Guillermo Almada Away Manager: Victor Vucetich
Head to Head
| Mexico Liga MX | 2018/11/04 22:00 | Queretaro v Santos Laguna | L | 2-1 |
| Mexico Liga MX | 2018/04/08 23:00 | Santos Laguna v Queretaro | W | 3-0 |
| Mexico Cup | 2018/03/14 03:15 | Santos Laguna v Queretaro | W | 1-0 |
| Mexico Liga MX | 2017/10/21 22:00 | Queretaro v Santos Laguna | W | 1-2 |
| Mexico Liga MX | 2017/04/02 23:00 | Santos Laguna v Queretaro | W | 1-0 |
| Mexico Liga MX | 2016/10/01 22:00 | Queretaro v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2016/01/30 03:30 | Santos Laguna v Queretaro | W | 2-0 |
| Mexico Liga MX | 2015/08/12 01:30 | Queretaro v Santos Laguna | W | 1-2 |
| Mexico Liga MX | 2015/06/01 01:30 | Queretaro v Santos Laguna | L | 3-0 |
| Mexico Liga MX | 2015/05/29 01:30 | Santos Laguna v Queretaro | W | 5-0 |
| Mexico Cup | 2015/03/04 03:00 | Santos Laguna v Queretaro | D | 2-2 |
| Mexico Cup | 2015/02/26 03:00 | Queretaro v Santos Laguna | L | 5-0 |
| Mexico Liga MX | 2015/01/31 01:30 | Queretaro v Santos Laguna | W | 0-1 |
| Mexico Liga MX | 2014/08/10 01:00 | Santos Laguna v Queretaro | L | 2-3 |