Buffalo 43-14 Eastern Michigan 2019-11-02 16:00
Stadium: Rynearson Stadium Round: 1
Home Manager: Chris Creighton Away Manager: Lance Leipold
Head to Head
| NCAAF | 2018/09/15 22:00 | Eastern Michigan v Buffalo | W | 28-35 |
| NCAAF | 2014/10/11 17:00 | Eastern Michigan v Buffalo | L | 37-27 |
| NCAAF | 2011/11/12 12:00 | Eastern Michigan v Buffalo | L | 30-17 |
| NCAAF | 2010/11/20 12:00 | Buffalo v Eastern Michigan | L | 17-21 |
| NCAAF | 2005/11/19 12:00 | Buffalo v Eastern Michigan | L | 14-38 |
| NCAAF | 2004/09/02 23:00 | Eastern Michigan v Buffalo | L | 37-34 |
| NCAAF | 2001/10/27 12:00 | Eastern Michigan v Buffalo | L | 24-20 |