[3] America de Cali 2-1 Atletico Nacional Medellin [1] 2019-10-19 22:00
Stadium: Olimpico Pascual Guerrero Round: 18
Referee: Carlos Mario Herrera Bernal Home Manager: Alexandre Guimaraes Away Manager: Juan Carlos Osorio
Head to Head
| Colombia Primera A | 2019/04/27 23:00 | Atletico Nacional Medellin v America de Cali | L | 2-0 |
| World Club Friendlies | 2019/01/15 00:00 | Atletico Nacional Medellin v America de Cali | W | 0-1 |
| Colombia Primera A | 2018/08/18 22:30 | America de Cali v Atletico Nacional Medellin | L | 0-2 |
| Colombia Primera A | 2018/02/23 00:05 | Atletico Nacional Medellin v America de Cali | L | 2-0 |
| Colombia Primera A | 2017/08/17 01:10 | Atletico Nacional Medellin v America de Cali | L | 2-0 |
| Colombia Primera A | 2017/03/05 22:15 | America de Cali v Atletico Nacional Medellin | D | 0-0 |